Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...
Patent
1994-07-20
1996-02-13
Lilling, Herbert J.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing heterocyclic carbon compound having only o, n, s,...
435117, 435122, C12P 1716, C12P 1712
Patent
active
054910773
ABSTRACT:
The present invention provides a process for the stereoselective reduction of phenylalkyl ketones to their corresponding (S)-hydroxy compounds. The process utilizes the novel microorganism Microbacterium MB 5614 to effectuate the chiral reduction. The present invention also provides said novel Microbacterium, which has been deposited with the ATCC and assigned the accession number ATCC 55557.
REFERENCES:
patent: 5270324 (1993-12-01), Zamboni et al.
Int'l. J. Syst. Bact. 43(3):549-554.
Bergey's Manual of Systematic Bacteriology vol. II 1320-22.
J. Org. Chem. 1993, 58, 3731-3735.
Chartrain Michel M.
Chen Shieh-Shung T.
Garrity George M.
Heimbuch Brian
Roberge Christopher
Lilling Herbert J.
Merck & Co. , Inc.
Rose David L.
Yang Mollie M.
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