Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1980-03-26
1981-05-05
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
A01N 1500, C09D 532, C12K 108
Patent
active
042658802
ABSTRACT:
An improved microbial insecticide composition, and methods for the production and utilization thereof, are disclosed. The disclosed composition comprises a microbial insect pathogen of viral, bacterial, or fungal origin which is susceptible to sunlight-induced inactivation embedded in a coacervate microbead which is comprised of a nucleic acid, typically RNA, and a proteinaceous material, whereby the microbead structure itself effectively shields the agent from sunlight-induced inactivation. The microbead is typically stabilized by chemical crosslinking.
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Evreinova T. N. et al. J. Colloid & Interface Sci., 36(1):18-23, May 1971, The Interaction of Biological Macro Molecules in Coacervate Systems.
Kreig, A. J. Invert. Pathol. 25:267-268 (1975), Photo Protection Against Inactivation of Bacillus Thuringionis Spores by Ultraviolet Rays.
WO 79/00155 5 Apr. 1979, PCT/US/78/00080, 12 Sep. 1978, Andrews Re. Spence KD. Microbial Insecticides Battelle Development Corp.
Andrews Robert E.
Spence Kemet D.
Battelle Development Corporation
Rose Shep K.
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