Microbial hybrid promoters

Details Microbial hybrid promoters Microbial hybrid promoters

1982-01-11

1985-11-05

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435 68, 435 70, 435 71, 4351723, 435317, 435849, 536 27, 935 38, 935 41, 935 61, 935 73, C12N 120, C12N 1500, C12N 100, C12P 2100, C12P 2102, C12P 2104, C07H 2104, C12R 119

Patent

active

045514330

ABSTRACT:
Novel microbial hybrid promoters and their use to direct the microbial expression of heterologous genes are described. Such promoters are selectively and functionally constructed by recombinant techniques, utilizing the discovery that certain DNA regions of given promoters are responsible for particularly advantageous functional properties.

REFERENCES:
Heynecker et al.: Nature 263, 748 (1976).
DeBoer et al.: In Promoters, Structure and Function, Rodriguez et al. (ed.), Praeger Scientific (1982), pp. 462-481.
Nagahari: J. Bacteriol. 136, 312, (1978).
Ihara et al.: Biochim., Biophys. Acta 432, 199 (1976).
DeBoer et al.: J. Biol. Chem. 254, 5609 (1979).
DeBoer et al.: Cell 17, 201 (1979).
Young et al.: Cell 17, 225 (1979).
Siebenlist et al.: Cell 20, 269 (1980).
Rosenberg et al.: Ann. Rev. Genet. 13, 319 (1979).
Hamming et al.: Nucl. Acids Res. 7, 1019 (1979).

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