Microbial biofilm removal methods and systems

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of...

Reexamination Certificate

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C134S001000, C134S001100, C510S108000, C510S109000, C510S161000

Reexamination Certificate

active

08076117

ABSTRACT:
Methods, kits, and systems for removing microbial biofilms from surfaces of objects (such as, e.g., explanted medical devices) are disclosed. The methods, kits, and systems rely on the use of acoustic energy in the presence of microbubbles to enhance biofilm removal while retaining viability of the microorganisms in the biofilm. The microbubbles may be provided in a variety of manners such as, e.g., vortexing a liquid, obtaining a suspension that includes pre-formed protein-stabilized microbubbles, etc.

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