Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2006-12-26
2006-12-26
Paras, Jr., Peter (Department: 1639)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
C435S007100, C435S287100, C435S287200, C435S288700, C435S091500, C435S091500, C435S091500, C435S091500, C435S091500, C436S518000, C436S524000, C436S525000, C436S527000, C436S535000
Reexamination Certificate
active
07153682
ABSTRACT:
Provided are peptidomimetic protein-binding arrays, their manufacture, use, and application. The protein-binding array elements of the invention include a peptidomimetic segment linked to a solid support via a stable anchor. The invention contemplates peptidomimetic array element library synthesis, distribution, and spotting of array elements onto solid planar substrates, labeling of complex protein mixtures, and the analysis of differential protein binding to the array. The invention also enables the enrichment or purification, and subsequent sequencing or structural analysis of proteins that are identified as differential by the array screen. Kits including proteomic microarrays in accordance with the present invention are also provided.
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Beausoleil Eric
Charych Deborah
Zuckermann Ronald N.
Austin James E.
Chiron Corporation
Harbin Alisa A.
Paras, Jr. Peter
Suh Young J.
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