Microarray having a base cleavable sulfonyl linker

Details Microarray having a base cleavable sulfonyl linker Microarray having a base cleavable sulfonyl linker

2006-02-24

2009-06-02

Riley, Jezia (Department: 1637)

Combinatorial chemistry technology: method, library, apparatus

Library, per se

C506S016000, C506S019000, C506S023000, C435S006120, C536S023100, C536S024300, C536S025300

Reexamination Certificate

active

07541314

ABSTRACT:
The present invention provides a microarray having base cleavable, sulfonyl-containing linkers and a process to make the microarray. Oligonucleotides of any sequence may be synthesized on the microarray having the cleavable linker. The oligonucleotides may be cleaved and recovered as a pool of oligonucleotides having a three prime phosphate moiety. Specifically, the microarray is an electrode containing microarray, and the oligonucleotides are electrochemically synthesized.

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