Micro- or nano-fluidic chip fabricated with Norland Optical...

Adhesive bonding and miscellaneous chemical manufacture – Methods – Surface bonding and/or assembly therefor

Reexamination Certificate

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Details

C422S502000, C422S068100, C422S130000, C156S261000, C156S510000, C436S003000, C436S043000, C216S024000, C216S033000, C216S037000

Reexamination Certificate

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07981237

ABSTRACT:
A micro- or nano-fluidic chip fabricated with a Norland Optical Adhesive (NOA), an acrylated polyurethane-based UV-polymerizable optical adhesive. The micro- or nano-fluidic chip has sequentially an inlet, a channel, and an outlet. The channel has a pillar in the region of the outlet to prevent beads from flowing out, and the surface of the channels in the micro- or nano-fluidic chip is hydrophilic, which generates spontaneous flow in the channels by a capillary force without any extra external pumping.

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patent: 6645432 (2003-11-01), Anderson et al.
patent: 2003/0161572 (2003-08-01), Johnck et al.
patent: 2004/0134882 (2004-07-01), Mei
Odemir et al., Oxygen Plasma Modification of Polyurethane Membranes, 2002, vol. 13, pp. 1147-1152.
Rohit Pal, et al., “An integrated microfluidic device for influenza and other genetic analyses”, Lap Chip (2005) vol. 5, pp. 1-9.
So Hyun Kim, et al., “Simple route to hydrophilic microluidic chip fabrication using an ultraviolet (UV)-cured polymer”, Adv. Funct. Mater. (2007) in press.
Pal, et al., An Integrated Microfluidic Device for Influenza and Other Genetic Analyses, Lab on a Chip, 2005, 5:1-9.
Bartolo, et al., Microfluidic Stickers, Lab Chip, 2008, 8:274-279.

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