Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules
Patent
1996-04-05
1997-05-27
Azpuru, Carlos A.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Capsules
424433, 424443, 424464, A61K 948, A61K 920, A61K 970
Patent
active
056330120
ABSTRACT:
Micro-encapsulated lactobacilli bacteria are orally administered to mammals, including humans, to treat or prevent antibiotic associated or other chronic or acute diarrhea. Micro-encapsulated lactobacilli bacteria are topically administered to the skin to treat or prevent recurrent skin infections, and are administered intra-vaginally to treat or prevent vaginal yeast infections.
REFERENCES:
patent: 4579734 (1986-04-01), Hata et al.
patent: 4983163 (1991-01-01), Winans, Jr. et al.
Monif, Gilles R.G. et al. "Quantitative and qulitative effects of poyidone-iodine liquid and gel on the aerobic and anaerobic flora of the female genital tract", Am.J. Obstet. Gynecol. 137(4): 432-438 (Jun. 15, 1980).
McGroarty, Jacqueline A. et al. "Development of Lactobacillus Probiotics", Clinical Advances in the Treatment of Infections, New York, pp. 16, 13-14.
McGroarty, Jacqueline A. and Moody, KarenJ., "Nonoxynol-9 and Urogenital Infections in Women", Clinical Advances in the Treatment of Infections, pp. 16, 12-14.
Sherris, Jacqueline D. et al. "New Developments in Vaginal Contraception", Population Reports, (By Population Information Program, The Johns Hopkins University), 12(1): H-159-191 (1984).
McGroarty, Jacqueline A. et al. "Influence of the spermicidal compound Nonoxynol-9 on the growth and Adhesion of Urogenital bacteria in vitro", Current Microbiology, vol. 21 (1990), 219-223.
McGroarty, Jacqueline A. et al. "Hydrogen Peroxide Production by Lactobaillus Species: Correlation with Susceptibility to the Spermicidal Compound Nonoxyno-9", JID, 1992:165 (Jun.), 1142-1144.
McGroarty, J.A. et al. "Influence of the Spermicidal Compound Nonoxynol-9 on the Adhesion of E coli to Human Epithelial Cells", Int Urogynecol J, (1993)4: 194-198.
McGroarty, J.A. et al. "Modulation of Adhesion of Uropathogenic Enterococcus faecalis to Human Epithelia Cells in vitro by Lactobacillus species", Microbial Ecology in Health and Disease, vol. 5: 309-314 (1992).
McGroarty, Jacqueline A. et al. "The Spermicidal Compound Nonoxynol-9 Increases Adhesion of Candida Species to Human Epithelial Cells in Vitro", Infection and Immunity, 58(6): pp. 2005-2007, (Jun., 1990).
Kreiss, Joan et al. "Efficacy of Nonoxynol 9 Contraceptive Sponge Use in Preventing Heterosexual Acquisition of HIV in Nairobi Prostitutes", JAMA, Jul. 22/29, 1992, 268(4): 447-482.
Goldin, Barry R. and Gorbach, Sherwood L. "Alterations of the IntestinalMicroflora by Diet, Oral Antibiotics, and Lactobacillus: Decreased Production of Free Amines From Aromatic Nitro Compounds, Azo Dyes, and Glucuronides", JNCI, 73(3): 689-695 (Sep. 1984).
Barefoot, Susan F. and Klaenhammer, Todd R. "Detection and Activity of Lactacin B, a Bacteriocin Produced by Lactobacillus acidophilus", Applied and Environmental Microbiology, 45(6):1808-1815 (Jun. 1983).
Barefoot, Susan F. and Klaenhammer, Todd R. "Purification and Characterization of the Lactobacillus acidophilus Bacteriocin Lactacin B", Antimicrobial Agents and Chemotherapy, 26(3): pp. 328-334 (Sep. 1984).
Mehta, A.M. et al. "Purification and properties of the inhibitory protein isolated from Lactobacillus acidophilus AC", Microbios, 38: pp. 73-81 (1983).
Silva, M. et al. "Antimicrobial Substance from a Human Lactobacillus Strain", Antimicrobial Agents and Chemotherapy, 31(8): pp. 1231-1233 (Aug. 1987).
S. Leodolter, E. Reinold et al. "Ceftriaxon, I g i.v.-Effectively Prevents Infections And Is Cost Effective", Program and Abstras--3rd World Congress for Infectious Diseases in Obstetrics and Gynecology combined with Infectious Diseases in Urology, Dermatology, and Clinical Immunology, Acapulco, Mexico, 1993. p. 110.
Ford, L.C. et al. "In Vitro Antimicrobial Effects of the Inner Confidence Lactobacilli (Lactobacillus Acidophilus 6 Lactobacillus Rhamnosus)" Program And Abstrats--3rd World Congress for Infectious Diseases in Obstetrics and Gynecology combined with InfectiousDiseases in Urology, Dermatology and Clinical Immunology, Acapulco, Mexico, 1993, p. 110.
Ford L.C. et al. "Safety of Inner Confidence Supporitories", Proram And Abstracts--3rd World Congress for Infectious Diseases in Obstetrics and Gynecology combined with Infectious Diseases in Urology, Dermatology and Clinical Immunology, Acapulco, Mexico, 1993, p. 111.
Ford, L.C. et al. "Topical Therapy of Bacterial Vaginosis", Program and Abstracts--1st World Congress for Infectious Diseases in Obstetrics and Gynecology, Hawaii, USA, 1989, p. 78.
Azpuru Carlos A.
Lafor Laboratories Limited
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