Micro-dispenser for preparing assay plates

Details Micro-dispenser for preparing assay plates Micro-dispenser for preparing assay plates

1995-03-10

1996-09-03

Recla, Henry J.

Fluent material handling, with receiver or receiver coacting mea

Processes

Battery grid pasting

141130, 422100, 436180, B65B 4342, B67C 300

Patent

active

055514871

ABSTRACT:
A method and apparatus for dispensing immobilized reactants onto substrates for use in generating a biological assay plate for detecting the presence of mobile reactants that bind to the immobilized reactants. The apparatus includes a dispensing bed that holds a plurality of substrates. Each potential immobilized reactant is held in a cartridge. The apparatus includes a holder that allows any of these cartridges to be used in dispensing an immobilized reactant. The apparatus includes a positioning mechanism for positioning the cartridges over each of the substrates. The positioning mechanism also allows a cartridge so positioned to be brought into contact with each of the substrates at a predetermined location on each of the substrates so as to dispense a known quantity of the immobilized reactant onto the substrate at that location. In the preferred embodiment of the present invention, the cartridges include a chamber for holding the immobilized reactant and a channel having a first end communicating with the chamber. The second end of the channel provides the exit path through which the immobilized reactant exits when the cartridge is brought into contact with the substrates.

REFERENCES:
patent: 2874734 (1959-02-01), Luckock et al.
patent: 4041995 (1977-08-01), Columbus
patent: 4632808 (1986-12-01), Yamamoto et al.
patent: 4699884 (1987-10-01), Noss et al.
patent: 5046539 (1991-09-01), MacLeish et al.
patent: 5443791 (1995-08-01), Cathcart et al.

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