Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...
Reexamination Certificate
2009-01-30
2010-10-26
Choi, Ling-Siu (Department: 1796)
Synthetic resins or natural rubbers -- part of the class 520 ser
Synthetic resins
Mixing of two or more solid polymers; mixing of solid...
Reexamination Certificate
active
07820759
ABSTRACT:
A novel micellar preparation in which the solubility of a sparingly water-soluble anticancer agent has been heightened and which after intravenous administration, enables a high blood concentration to be maintained. The preparation has high medicinal activity and/or is reduced in side effects. The micellar preparation is formed from a block copolymer represented by the following general formula (1):[wherein R1 represents hydrogen or C1-5alkyl; R2 represents C1-5alkylene; R3 represents methylene or ethylene; R4 represents hydrogen or C1-4acyl; R5 represents hydroxyl, optionally substituted aryl C2-8alkoxyl, substituted C1-4alkylamino, or amino having a residue of either an amino acid or a peptide derivative; n is an integer of 5 to 1,000; m is an integer of 2 to 300; and x is an integer of 1 to 300; provided that the proportion of hydroxy in the R5's is 0 to 99% and x is not larger than m] and a sparingly water-soluble anticancer agent.
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Murata Toshitaka
Sagawa Katsuhiko
Shimizu Kazuhisa
Choi Ling-Siu
Nanocarrier Kabushiki Kaisha
Nields, Lemack & Frame, LLC
Nippon Kayaku Kabushiki Kaisha
Wright Sonya
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