MHC eukaryotic promoter

Details MHC eukaryotic promoter MHC eukaryotic promoter

1994-01-11

1995-08-15

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Vector, per se

536 241, C12N 1585, C12N 1511

Patent

active

054418895

ABSTRACT:
A promoter/enhancer for a bovine MHC class I gene is incorporated in recombinant nucleotide sequences and vectors. In one form, the promoter/enhancer may be linked to a foreign gene for permitting expression of the foreign gene in a wide range of mammalian host cells.

REFERENCES:
Ovnic et al. 1991, Genomics 11:956-967.
Koller et al. 1985, J. of Immunology, 134(4):2727-2733.
T. Garber, et al., "Sequence and evolution of cattle MHC class I cDNAS: concerted evolution has not taken place in cattle", 38 Immunogenetics, 11-20 (1993).
A. Bensaid, et al., "Identification of expressed bovine class I MHC genes at two loci and demonstration of physical linkage", 33 Immunogenetics, 247-254 (1991).
P. Ennis, et al., "Molecular Cloning of Bovine Class I MHC cDNA", 141 J. Immunol, 642-651 (1988).
P. Brown, et al., "Cloning and characterization of a BoLA class I cDNA clone", 29 Immunogenetics, 58-60 (1989).
R. Hakem, et al., "Differential Regulation of HLA-A3 and HLA-B7 MHC Class I Genes by IFN . . . ", 147 J. Immunol., 2384-2390 (1991).
A. Kimura, et al., "Detailed Analysis of the Mouse H-2K.sup.b Promoter . . . ", 44 Cell, 261-272 (1986).
J. Weissman, et al., "A Complex Regulatory DNA Element Associated with a MHC Class I Gene . . . ", 11 Mol. Cell. Biol., 4217-4227 (1991).
M. Kay, et al., "In Vivo Gene Therapy of Hemophilia B . . . ", 262 Science, 117-119 (1993).
J. Marx, "A First Step Toward Gene Therapy for Hemophilia B?", 262 Science, 29-30 (1993).
M. Manthorpe, et al., "Gene Therapy by Intramuscular Injection of Plasmid DNA . . . ", 4 Human Gene Therapy, 419-431 (1993).

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