Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 8 to 10 amino acid residues in defined sequence
Reexamination Certificate
2005-10-04
2005-10-04
Chan, Christina (Department: 1644)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
8 to 10 amino acid residues in defined sequence
C530S324000, C530S325000, C530S326000, C530S327000, C530S350000, C530S402000, C530S403000, C424S185100, C424S192100, C424S193100, C424S277100, C424S093710
Reexamination Certificate
active
06951917
ABSTRACT:
The present invention provides MHC Class II restricted melanoma antigens recognized by CD4+T cells. This invention further provides prophylactic and therapeutic applications for the Class II restricted melanoma antigens. In particular, this invention provides tyrosinase Class II restricted melanoma antigens, as well as tyrosinase immunogenic peptides which have been modified to enhance their immunogenicity. These antigens can serve as an immunogens or vaccines to prevent or treat melanoma. In addition a method for isolating Class II restricted melanoma antigens or identifying new Class II restricted melanoma antigens is provided.
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Robbins Paul F.
Rosenberg Steven A.
Topalian Suzane L.
Chan Christina
The United States of America as represented by the Department of
Vandervegt F. Pierre
LandOfFree
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