MHC class II .beta. chain/peptide complexes useful in ameliorati

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...

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4241851, 4241931, 530300, 530395, 530402, 530868, C07K 1474, C07K 1700, A61K 39385

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057340234

ABSTRACT:
The present invention is directed to complexes comprising an isolated MHC subunit component, an antigenic peptide and, in some cases, an effector component. The antigenic peptide is associated with the antigen binding site of the MHC subunit component. These complexes are useful in treating autoimmune disease.

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