MHC-antigen arrays for detection and characterization of...

Combinatorial chemistry technology: method – library – apparatus – Method specially adapted for identifying a library member – Identifying a library member by means of a tag – label – or...

Reexamination Certificate

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C506S002000, C506S003000, C506S033000, C506S035000, C435S286300, C435S283100, C435S305200

Reexamination Certificate

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07902121

ABSTRACT:
T cells are profiled with respect to their expression of antigen receptor. The cells are arrayed on a planar or three-dimensional substrate through binding to immobilized or partially diffused MHC-antigen complexes. The cells may further be characterized with respect to their ability to respond to external stimulus in the microenvironment. External stimuli include cell-cell interactions, response to factors, and the like.

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