MGDF analogs

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.

Reexamination Certificate

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C435S069500

Reexamination Certificate

active

07399833

ABSTRACT:
MGDF analogs having one or more changed glycosylation sites as compared to a naturally occurring MGDF sequence of a corresponding number of amino acids are disclosed. The invention also relates to DNA sequences encoding said MGDF analogs, recombinant plasmids and host cells for analog expression, and therapeutic compositions including such analogs.

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Bose et al. (1976) J. of Biol. Chem. vol. 251, No. 6, pp. 1659-1662.
Chang et al. (1995) J. of Biol. Chem. vol. 270, No. 2, pp. 511-514.
Delorme et al. (1992)Biochemistry31/41:9871-9876.

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