Metod for the synthesis of perindopril and the...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S452000

Reexamination Certificate

active

10570566

ABSTRACT:
A process for the synthesis of perindopril of formula (I):and its pharmaceutically acceptable salts.

REFERENCES:
patent: 49658 (1982-04-01), None
patent: 1319668 (2003-06-01), None
patent: 1321471 (2003-06-01), None
patent: 1371659 (2003-12-01), None
M.A. Huffman, et al., “Improved stereoselectivity in the heterogeneous catalytic synthesis of enalapril obtained through multidimensional screening” Tetrahedron Letters, vol. 40 No. 5 pp. 831-834, Jan. 29, 1999.
T.J. Blacklock, et al., “Synthesis of semisynthetic dipeptides using N-carboxxanhydrides andchiral induction of raney nickel. A method practical for large scale” Journal of Organic Chemistry, vol. 53 No. 4, pp. 836-844, 1988.
International Search Report for PCT/FR2004/002196, Feb. 3, 2005.
European Search Report for EP 03292132, Nov. 18, 2003.

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