Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-06-15
1999-11-09
Davis, Zinna Northington
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549477, C07D30702, A61K 3134
Patent
active
059815760
ABSTRACT:
The invention encompasses the novel compound of Formula A that is useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula A.
REFERENCES:
patent: 5474995 (1995-12-01), Ducharme et al.
patent: 5480568 (1996-01-01), Pawloski et al.
James J. Li, et al., J. of Med Chem., vol. 38, No. 22, pp. 4570-4578 (1995) .
Belley Michel
Black Cameron
Gauthier Jacques Yves
Grimm Erich
Lau Cheuk-Kun
Billups Richard C.
Davis Zinna Northington
Merck Frosst Canada Inc.
Rose David L.
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