(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514312, 514336, 514438, 514461, 514473, 514604, 514708, 514741, 514764, 546142, 546153, 5462844, 549 78, 549475, 564 12, 564 90, 568 17, 568 34, C07D30762, A61K 31665

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active

060203439

ABSTRACT:
The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.

REFERENCES:
patent: 5474995 (1995-12-01), Ducharme et al.
patent: 5480568 (1996-01-01), Pawloski et al.

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