Methylobacterium extorquwns microorganism useful for the prepara

Details Methylobacterium extorquwns microorganism useful for the prepara Methylobacterium extorquwns microorganism useful for the prepara

1992-11-23

1994-04-12

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435136, 435822, C12N 112, C12R 101, C12P 740

Patent

active

053025253

ABSTRACT:
The present invention relates to a type of polymer comprising repeating units of formula ##STR1## and in particular to a poly-.beta.-hydroxybutyrate polyester type polymer. The present invention also relates to a microbiological process for the production of the above type of polymer, to a methylotrophic microorganism (bacterium) for use in such a process, and to means for controlling such bioprocesses.

REFERENCES:
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Poly-B-Hydroxybutyrate contents of methylotrophic bacteria with different routes for methanol assimilation, Govorukhina and Trotsenko, vol. 27, No. 1, 1988.
Polyhydroxybutyrate: an Intriguing biopolymer, Dawes, Bioscience Reports, vol. 8, No. 6, 1988.
A survey of the accumulation of novel polyhydroxyalkanoates by bacteria, Haywood, Anderson and Dawes, Biotechnology Letter, vol. 11, No. 7, 471-476 (1989).
Mass production of poly-B-hydroxybutyric acid by fully automatic fed-batch culture of methylotroph, Suzuki, Yamane and Shimizu, Applied and Microbiology Biotechnology, (1986) 23:322-329.
Kinetics and effect of nitrogen source feeding on production of poly-B-hydroxybutyric acid by fed-batch culture, Suzuki, Yamane and Shimizu, Applied and Microbiology Biotechnology, (1986)24:366-369.
Mass production of poly-B-hydroxybutyric acid by fed-batch culture with controlled carbon
itrogen feeding, Suzuki, Yamane and Shimizu, Applied and Microbiology Biotechnology, (1986)24:370-374.
Control of molecular weight of poly-B-hydroxybutyric acid produced in fet-batch culture of Protomonas extroquens, Suzuki, Deguchi, Yamane, Shimizu and Gekko, Applied and Microbiology Biotechnology, (1988)27:487-491.
Studies on the Growth-associated Accumulation of Poly-B-hydroxybutyric Acid with Methylobacterium rhodesiamun Z, Hilger, Sattler and Littkowsky, Zentralbl. Mikrobiol. 146(1991), 83-88.
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Manufacture of containers from an oriented biopolymer, Reyman, Koch and Albrecht, Technische Mitteilungen Krupp, No. 2, pp. 113-118, 1990.
PHB recovery by hypochlorite digestion of non-PHB biomass, Berger, Ramsay, Ramsay and Chavarie, Biotechnology Techniques, vol. 3, No. 4, pp. 227-232, 1989.
Production of poly-.beta.-hydroxybutyrate from methanol: characterization of a new isolate of Methylobacterium extorquens, Bourque et al., (Apr., 1992), Appl. Microbiol. Biotechnol., vol. 37, pp. 7-12.
Solution properties of poly(D-.beta.-hydroxybutyrate). I. Biosynthesis and characerization, Akita et al. 1976, Macromolecules, vol. 9, pp. 774-780.
Occurrence, metabolism, metabolic role, and industrial uses of bacterial polyhydroxyalkanoates, Anderson and Dawes, (1990), Microbiological Rev., vol. 54, No. 4, pp. 350-472.
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