Methyl 2-[(3S)-[3-[2E)-(7-chloro quinolin-2-yl) ethenyl]...

Details Methyl 2-[(3S)-[3-[2E)-(7-chloro quinolin-2-yl) ethenyl]... Methyl 2-[(3S)-[3-[2E)-(7-chloro quinolin-2-yl) ethenyl]...

2004-07-19

2010-12-28

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S163000

Reexamination Certificate

active

07858793

ABSTRACT:
The present invention relates to the novel compounds Methyl 2-[(3S)-[3-[(2E)(7-chloro quinolin-2-yl)ethenyl]phenyl]-3-halopropyl]benzoates (IV) wherein the halo is chloro, bromo, iodo, starting from the known compound Methyl 2-[(3S)-[3-[(2E)-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-hydroxypropyl]benzoate (1). Reaction of Methyl 2-[(3S)-[3-[(2E)-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-hydroxypropyl]benzoate (1) with thionyl chloride or with methane sulfonyl chloride-lithium bromide or with trimethyl chlorosilane-sodium iodide in presence or absence of base gives Methyl 2-[(3S)-[3-[(2E)-(7-chloro quinolin-2-yl)ethenyl]phenyl]-3-halopropyl]benzoates.

REFERENCES:
patent: 5565473 (1996-10-01), Belley et al.
patent: 5614632 (1997-03-01), Bhupathy et al.
patent: 7501517 (2009-03-01), Overeem et al.
patent: 0 480 717 (1992-04-01), None
Yoshida, Tetrahedron, vol. 55, pp. 2183-2192, 1999.

Affiliated with

Also associated with

Rating

Methyl 2-[(3S)-[3-[2E)-(7-chloro quinolin-2-yl) ethenyl]... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methyl 2-[(3S)-[3-[2E)-(7-chloro quinolin-2-yl) ethenyl]..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methyl 2-[(3S)-[3-[2E)-(7-chloro quinolin-2-yl) ethenyl]... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4161127