Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Lipid or oil
Patent
1981-12-21
1984-06-12
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Nonspecific immunoeffector, per se ; or nonspecific...
Lipid or oil
424 78, A61K 3135
Patent
active
044541520
ABSTRACT:
This invention relates to oral dosage forms wherein the active ingredient, methoxsalen, is dispersed in a water-soluble composition containing a polyethylene glycol or mixtures of polyethylene glycols. Dissolution of methoxsalen in gastrointestinal fluids as well as drug absorption are more rapid and higher blood level patterns are achieved with these dosage forms as compared to conventional encapsulated dosage forms.
REFERENCES:
patent: 3972999 (1976-08-01), Tsuk
patent: 4130568 (1978-12-01), Confolone et al.
Chemical Abstracts 85: 99195g (1926).
Chemical Abstracts 81: 96386b (1924).
Barry Richard H.
Lazarus Jack H.
Hoffmann-La Roche Inc.
Leon Bernard S.
Manning Elizabeth
Saxe Jon S.
Schenkman Leonard
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