Methoxsalen dosage forms

Details Methoxsalen dosage forms Methoxsalen dosage forms

1981-12-21

1984-06-12

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

Lipid or oil

424 78, A61K 3135

Patent

active

044541520

ABSTRACT:
This invention relates to oral dosage forms wherein the active ingredient, methoxsalen, is dispersed in a water-soluble composition containing a polyethylene glycol or mixtures of polyethylene glycols. Dissolution of methoxsalen in gastrointestinal fluids as well as drug absorption are more rapid and higher blood level patterns are achieved with these dosage forms as compared to conventional encapsulated dosage forms.

REFERENCES:
patent: 3972999 (1976-08-01), Tsuk
patent: 4130568 (1978-12-01), Confolone et al.
Chemical Abstracts 85: 99195g (1926).
Chemical Abstracts 81: 96386b (1924).

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