Methods to treat alzheimer's disease

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S231200, C514S451000, C514S461000

Reexamination Certificate

active

07119085

ABSTRACT:
The present invention is directed toward substituted hydroxyethylene compounds of formula (XII)useful in treating Alzheimer's disease and other similar diseases.

REFERENCES:
patent: 4224179 (1980-09-01), Schneider
patent: 4231877 (1980-11-01), Yamauchi et al.
patent: 4235871 (1980-11-01), Papahadjopoulos et al.
patent: 4247411 (1981-01-01), Vanlerberghe et al.
patent: 4394448 (1983-07-01), Szoka, Jr. et al.
patent: 4399216 (1983-08-01), Axel et al.
patent: 4522811 (1985-06-01), Eppstein et al.
patent: 4616088 (1986-10-01), Ryono et al.
patent: 4636491 (1987-01-01), Bock et al.
patent: 4665193 (1987-05-01), Ryono et al.
patent: 4668770 (1987-05-01), Boger et al.
patent: 4673567 (1987-06-01), Jizomoto
patent: 4676980 (1987-06-01), Segal et al.
patent: 4736866 (1988-04-01), Leder et al.
patent: 4749792 (1988-06-01), Natarajan et al.
patent: 4753788 (1988-06-01), Gamble
patent: 4814270 (1989-03-01), Piran
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 4870009 (1989-09-01), Evans et al.
patent: 4880781 (1989-11-01), Hester, Jr. et al.
patent: 4897355 (1990-01-01), Eppstein et al.
patent: 5010182 (1991-04-01), Brake et al.
patent: 5142056 (1992-08-01), Kempe et al.
patent: 5145684 (1992-09-01), Liversidge et al.
patent: 5162538 (1992-11-01), Voges et al.
patent: 5175281 (1992-12-01), McCall et al.
patent: 5250565 (1993-10-01), Brooks et al.
patent: 5364934 (1994-11-01), Drayna et al.
patent: 5374652 (1994-12-01), Buzzetti et al.
patent: 5376542 (1994-12-01), Schlegal
patent: 5387742 (1995-02-01), Cordell
patent: 5441870 (1995-08-01), Seubert et al.
patent: 5461067 (1995-10-01), Norbeck et al.
patent: 5475138 (1995-12-01), Pal et al.
patent: 5481011 (1996-01-01), Chen et al.
patent: 5482947 (1996-01-01), Talley et al.
patent: 5502061 (1996-03-01), Hui et al.
patent: 5502187 (1996-03-01), Ayer et al.
patent: 5508294 (1996-04-01), Vazquez et al.
patent: 5510349 (1996-04-01), Talley et al.
patent: 5510388 (1996-04-01), Vazquez et al.
patent: 5516784 (1996-05-01), Bennett et al.
patent: 5521219 (1996-05-01), Vazquez et al.
patent: 5545640 (1996-08-01), Beaulieu et al.
patent: 5593846 (1997-01-01), Schenk et al.
patent: 5602169 (1997-02-01), Hewawasam et al.
patent: 5602175 (1997-02-01), Talley et al.
patent: 5604102 (1997-02-01), McConlogue et al.
patent: 5610190 (1997-03-01), Talley et al.
patent: 5612486 (1997-03-01), McConlogue et al.
patent: 5625031 (1997-04-01), Webster et al.
patent: 5631405 (1997-05-01), Pal et al.
patent: 5639769 (1997-06-01), Vazquez et al.
patent: 5648511 (1997-07-01), Ng et al.
patent: 5663200 (1997-09-01), Bold et al.
patent: 5708004 (1998-01-01), Talley et al.
patent: 5720936 (1998-02-01), Wadsworth et al.
patent: 5721130 (1998-02-01), Seubert et al.
patent: 5733882 (1998-03-01), Carr et al.
patent: 5744346 (1998-04-01), Chrysler et al.
patent: 5753652 (1998-05-01), Fässler et al.
patent: 5760064 (1998-06-01), Vazquez et al.
patent: 5760076 (1998-06-01), Vazquez et al.
patent: 5766846 (1998-06-01), Schlossmacher et al.
patent: 5807870 (1998-09-01), Anderson et al.
patent: 5807891 (1998-09-01), Bold et al.
patent: 5811633 (1998-09-01), Wadsworth et al.
patent: 5827891 (1998-10-01), Dressman et al.
patent: 5830897 (1998-11-01), Vazquez et al.
patent: 5831117 (1998-11-01), Ng et al.
patent: 5847169 (1998-12-01), Nummy et al.
patent: 5849911 (1998-12-01), Fässler et al.
patent: 5850003 (1998-12-01), McLonlogue et al.
patent: 5863902 (1999-01-01), Munoz et al.
patent: 5877015 (1999-03-01), Hardy et al.
patent: 5877399 (1999-03-01), Hsiao et al.
patent: 5912410 (1999-06-01), Cordell
patent: 5922770 (1999-07-01), Peschke et al.
patent: 5935976 (1999-08-01), Bold et al.
patent: 5942400 (1999-08-01), Anderson et al.
patent: 5965588 (1999-10-01), Vazquez et al.
patent: 6001813 (1999-12-01), Gyorkos et al.
patent: 6013658 (2000-01-01), Lau et al.
patent: 6022872 (2000-02-01), Vazquez et al.
patent: 6045829 (2000-04-01), Liversidge et al.
patent: 6051684 (2000-04-01), McDonald et al.
patent: 6060476 (2000-05-01), Vazquez et al.
patent: 6150344 (2000-11-01), Carroll et al.
patent: 6153652 (2000-11-01), Wu et al.
patent: 6191166 (2001-02-01), Audia et al.
patent: 6221670 (2001-04-01), Cordell et al.
patent: 6737420 (2004-05-01), Hom et al.
patent: 3 610 593 (1987-10-01), None
patent: 3 721 855 (1988-09-01), None
patent: 4 003 575 (1991-08-01), None
patent: 0 036 776 (1981-09-01), None
patent: 0 073 657 (1983-03-01), None
patent: 0 117 058 (1984-08-01), None
patent: 0 117 060 (1984-08-01), None
patent: 0 173 441 (1986-05-01), None
patent: 0 209 897 (1987-01-01), None
patent: 0 212 903 (1987-03-01), None
patent: 0 264 106 (1988-04-01), None
patent: 0 274 259 (1988-07-01), None
patent: 0 320 205 (1989-06-01), None
patent: 0 337 714 (1989-10-01), None
patent: 0 362 179 (1990-04-01), None
patent: 0 372 537 (1990-06-01), None
patent: 0 437 729 (1991-07-01), None
patent: 0 609 625 (1994-08-01), None
patent: 0 652 009 (1995-05-01), None
patent: 2 203740 (1988-10-01), None
patent: 2 211 504 (1989-07-01), None
patent: 62-246546 (1987-10-01), None
patent: 7-126286 (1995-05-01), None
patent: WO 87/02986 (1987-05-01), None
patent: WO 87/04349 (1987-07-01), None
patent: WO 87/05330 (1987-09-01), None
patent: WO 89/00161 (1989-01-01), None
patent: WO 89/01488 (1989-02-01), None
patent: WO 89/05859 (1989-06-01), None
patent: WO 90/13646 (1990-11-01), None
patent: WO 91/00360 (1991-01-01), None
patent: WO 92/00750 (1992-01-01), None
patent: WO 92/17490 (1992-10-01), None
patent: WO 92/20373 (1992-11-01), None
patent: WO 93/02057 (1993-02-01), None
patent: WO 93/08829 (1993-05-01), None
patent: WO 93/17003 (1993-09-01), None
patent: WO 94/04492 (1994-03-01), None
patent: WO 95/06030 (1995-03-01), None
patent: WO 97/30072 (1997-08-01), None
patent: WO 98/22597 (1998-05-01), None
patent: WO 98/29401 (1998-07-01), None
patent: WO 98/33795 (1998-08-01), None
patent: WO 98/50342 (1998-11-01), None
patent: WO 99/41266 (1999-08-01), None
patent: WO 99/54293 (1999-10-01), None
patent: WO 00/17369 (2000-03-01), None
patent: WO 00/47618 (2000-08-01), None
patent: WO 00/56335 (2000-09-01), None
patent: WO 00/61748 (2000-10-01), None
patent: WO 00/69262 (2000-11-01), None
patent: WO 00/77030 (2000-12-01), None
patent: WO 01/00663 (2001-01-01), None
patent: WO 01/00665 (2001-01-01), None
patent: WO 01/10387 (2001-02-01), None
patent: WO 01/19797 (2001-03-01), None
patent: WO 01/23533 (2001-04-01), None
patent: WO 01/29563 (2001-04-01), None
patent: WO 01/51659 (2001-07-01), None
Alterman et al.,J. Med. Chem,1998, 41, 3782-3792 Design and Synthesis of New Potent C2-Symmetric HIV-1 Protease Inhibitors. Use of L-Mannaric Acid as a Peptidomimetic Scaffold.
Amblard et al.,J. Med. Chem., 1999, 42:20, pp. 4193-4201 Synthesis and Characterization fo Bradykinin B2Receptor Agonists Containing Constrained Dipeptide Mimics.
Balicki et al.,Synth. Comm., 1993, 23(22), pp. 3149-3155 Mild and Efficient Conversion of Nitriles to Amides with Basic Urea-Hydrogen Peroxide Adduct.
Barton,Protective Groups in Organic Chemistry, 1976, Chpt. 2, pp. 43-93 Protection of N-H Bonds and NR.
Basu et al.,Tetrahedron Letters, 1998, 39, pp. 3005-3006 Efficient Transformation of Nitrile into Amide under Mild Condition.
Bennett et al.,Synlett, 1993, 9, pp. 703-704 The Synthesis of Novel HIV-Protease Inhibitors via Silica Gel Asisted Addition of Amines to Epoxides.
Berge et al.,Journal of Pharmaceutical Sciences, Jan. 1977, 66:1, pp. 1-19 Pharmaceutical Salts.
Bodendorf et al.,The Journal of Biological Chemistry, 2001, 276:15, pp. 12019-12023 A Splice Variant of β-Secretase Deficient in the Amyloidogenic Processing of the Amyloid Precursor Protein.
Bose et al.,Synth. Comm., 1997, 27(18), pp. 3119-3123 A Facile Hydration of Ntiriles by Dimethyldioxirane.
Calderwood et al.,Tetrahedron Letters, 1997, 38:7, pp. 1241-1244 Organocerium Reactions of Benzamides and Thiobenzamides: A Direct Synthesis of Tertiary Carbinamines.
Chen et al.,Tetrahedron-Mannaric Acid Letters, 1997, 38:18, pp. 3175-3178 A Practical Method for the Preparation of α′-Chloroketones of N-Carbamate Protected-α-Aminoacids.
Ciganek,J.

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