Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1989-05-15
1992-09-15
Kepplinger, Esther L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 74, 43524027, 436518, 436548, 436813, 53038826, G01N 33543, G01N 33574, G01N 33573, G01N 33577
Patent
active
051477831
ABSTRACT:
A monoclonal antibody against human manganese-superoxide dismutase characterized in that it is produced by a cell line which has been obtained by immunization of a mouse with human Mn-SOD and then fusion of lymphocytes obtained from the mouse with mouse myeloma cells, and has high specificity against human Mn-SOD; a method for producing a monoclonal antibody against human Mn-SOD having high specificity against human Mn-SOD, which comprises culturing the cell line obtained by immunization of a mouse with human Mn-SOD and then cell fusion of lymphocytes obtained from the mouse with mouse myeloma cells; a kit for assaying human Mn-SOD, comprising:
REFERENCES:
Kawaguchi et al. J. Biol. Chem. 264(10):5762, 1989.
Iizuka et al. J. Natl. Cancer Inst 72(5):1043, 1984.
Iizuka Hokkaido J. Med. Sci. 59(6):739, 1985.
Kohler et al. Nature 256:495, 1975.
Oberley et al. Cancer Res. 39:1141, 1979.
Kumari et al. Indian J. Exp. Biol. 25(6):419, 1987.
Hifumi Emi
Ishikawa Mutsuo
Itoh Yukikatsu
Kawaguchi Tetsuo
Noji Shirou
Kepplinger Esther L.
Shah Arti
Ube Industries Ltd.
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