Methods to predict cholesterol elevation during...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C536S024300, C435S091200

Reexamination Certificate

active

07732134

ABSTRACT:
This invention provides methods to predict the degree of elevation of serum cholesterol levels in patients treated with immunosuppressive medication. This invention also provides treatment strategies based on these predictions and kits to carry out these methods.

REFERENCES:
patent: 6268142 (2001-07-01), Duff et al.
patent: 2003/0235890 (2003-12-01), Wyllie et al.
patent: 00/72015 (2000-11-01), None
patent: 97/06180 (2002-02-01), None
Pediatia Polska (2004) vol. 79, pp. 127-134).
Brenner et al (Trends in Genetics (2001) vol. 17, pp. 414-418).
Moore (Drug Safety (2001) vol. 24, pp. 755-766).
Hirschhorn et al. (Genetics in Medicine. vol. 4, No. 2, pp. 45-61, Mar. 2002).
Genecard (GC02M113303, Apr. 18, 2008, pp. 1-15).
El Omar (Nature (2000) vol. 404, pp. 398-402).
Matzkies (Transplantation proceedings (2002) vol. 34, pp. 1795-1796).
El-Omar, et al., “Interleukin-1 polymorphisms associated with increased risk of gastric cancer”, Nature, vol. 404 (2000).
Mattila, et al., “Association of an interleukin 1B gene polymorphism (-511) with Parkinson's disease in Finnish patients”, J. of Med. Genetics (2002).
Kerschdorfer, et al., “Lipoprotein(a) plasma concentration after renal transplantation: a prospective evaluation after 4 years of follow-up”, Atherosclerosis, vol. 144 (1999).
Database EMBL Online: Clark, et al., “Human gene for prointerleukin 1 beta”, Accession No. X04500-XP002276413 (1997).
Radeau, et al., “HDL cholesterol and TaqIB cholesteryl ester transfer protein gene polymorphism in renal transplant recipients”, Nephron, vol. 84 (2000).
Blum, Conrad B., “Effects of Sirolimus on Lipids in Renal Allograft Recipients: An Analysis Using the Framingham Risk Model”, American Journal of Transplantation, vol. 2, pp, 551-559, (2002).
El-Omar et al., “Interleukin-1 Polymorphisms Associated with Increased Risk of Gastric Cancer”, Nature, vol. 404, pp. 398-402, (2000).
Morrisett et al,, “Effects of Sirolimus on Plasma Lipids, Lipoprotein Levels, and Fatty Acid Metabolism in Renal Transplant Patients” Journal of Lipid Research, vol. 43, pp, 1170-1180, (2002).
Radeau, T. et al., “HDL Cholesterol and Taq1B Cholesteryl Ester Transfer Protein Gene Polymorphism in Renal Transplant Recipients”, Nephron, vol. 84, pp. 333-341, (2000).
Van Darnme-Lornbaerts, R., “Single dose pharmacokinetics and tolerability of everolimus in stable pediatric renal transplant patients”, Pediatric Transplantation, vol. 6, No. 2, pp. 147-152 (2002).
“Thrombosis and Circulation”, vol. 7, No. 2, pp. 164-168 (1999) and translation of Summary p. 164.
Official Action issued Jun. 12, 2009, in corresponding Japanese Patent Application 2004-539048.

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