Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2004-03-05
2008-12-30
Russel, Jeffrey E (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S012200, C514S013800, C514S021800, C514S078000
Reexamination Certificate
active
07470659
ABSTRACT:
The present invention addresses the treatment of age-related macular degeneration using regulation of pathogenic mechanisms similar to atherosclerosis. In further specific embodiments, compositions that increase reverse cholesterol transport are utilized as therapeutic targets for age-related macular degeneration. In a specific embodiment, the lipid content of the retinal pigment epithelium, and/or Bruch's membrane is reduced by delivering Apolipoprotein A1, particularly a mimetic peptide.
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Bailey Kathy R.
Duncan Keith G.
Ishida Brian Y.
Kane John P.
Schwartz Daniel M.
Fulbright & Jaworski LLP
Russel Jeffrey E
The Regents of the University of California
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