Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Reexamination Certificate
2005-03-15
2005-03-15
Horlick, Kenneth R. (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
C435S006120
Reexamination Certificate
active
06866996
ABSTRACT:
The present invention provides methods for identifying evolutionarily significant polynucleotide and polypeptide sequences in human and/or non-human primates which may be associated with a physiological condition, such as enhanced resistance to HCV infection. The invention also provides methods for identifying evolutionarily significant polynucleotides with mutations that are correlated with susceptibility to diseases, such as BRCA1 exon 11. The methods employ comparison of human and non-human primate sequences using statistical methods. Sequences thus identified may be useful as host therapeutic targets and/or in screening assays.
REFERENCES:
patent: 5602005 (1997-02-01), Herr et al.
patent: 5965352 (1999-10-01), Stoughton et al.
patent: 6743580 (2004-06-01), Messier et al.
patent: 120658 (1984-10-01), None
patent: WO9939006 (2000-07-01), None
Dennis (1999) Nat. Gen. 22:10.
Favre et al. (2001) CR Acad, Sci. 324:1141-1148.
Galun et al. (1995) J. Infectious Diseases 172:25-30.
Hacia et al. (Feb. 1998) Nat. Gen. 18:155-158.
Labonte et al. (2002) J. Med. Virol. 66:312-319.
Lanford et al. (1991) J. Med. Virology 34:148-153.
Mercer et al. (Aug. 2001) Nat. Med. 7(8):927-933.
Shen et al. (1998) Oncogene 17:3115-3124.
Shimizu et al. (Apr. 1985) Med. Sci. 82:2138-2142.
Takahashi et al. (1990) J. General Virology 71:2005-2011.
Thompson et al. (Apr. 1995) Nat. Gen. 9:444-450.
Walker (1997) Springer Semin Immunopathology 19(1):85-98.
Xu et al. (Mar. 1999) Mol. Cell 3:389-395.
Xu et al. (May 1999) Nat. Gen. 22: 37-43.
Alter et al. (1998) Science 226:549-552.
Burger et al. (1994) J. Mol. Evol. 39:255-267.
Edwards et al. (1995) Molecular Ecology 4:719-729.
Endo et al. (1996) Mol. Biol. Evol. 13:685-690.
Fournier et al. (1988) J. Gen. Virol. 79:2367.
Fultz et al. (1986) Journal of Virology 58:116-124.
Gibbons (Sep. 1998) Science 281: 1432-1434, website www.sciencemag.org.
Goodman et al. (1990) J. Mol. Evol. 30:260-266.
Goodwin et al. (1996) Mol. Biol. Evol. 13:346-358.
Herbert et al. (1996) Mol. Biol. Evol. 13:1054-1057.
Hughes (1997) Mol. Biol. Evol. 14:1-5.
Hughes and Nei (1988) Nature 335:167-170.
Huttley et al. (2000) Nature Genetics 25:410-13.
Jaeger et al. (1994) Immunogenetics 40:184-191.
Jenkins et al. (1995) Proc. R. Soc. Lond. 261:203-207.
Kitamura et al. (1994) Eur. J. Biochem. 224:877-83.
Kreitman and Akashi (1995) Annu. Rev. Ecol. Syst. 26:403-422.
Lee and Vacquier (1992) Biol. Bull. 182:97-104.
Lee et al. (1998) Aids Research and Human Retroviruses 14:1323-1328.
Li (1990) J. Mol. Evol. 36:96-99.
Li (1997) in Molecular Evolution, Sinauer Associates, Inc. Pub., Sunderland, MA, Table of Contents.
Li et al. (1985) Mol. Biol. Evol. 2:150-174.
Lienert and Parham (1996) Immunol. Cell Biol. 74:349-356.
Lyn et al. (1995) Gene 155:241-245.
Malcolm et al. (1990) Nature 345:86-89.
McDonald and Kreitman (1991) Nature 351:652-654.
Messier and Stewart (1994) Current Biology 4:911-913.
Messier and Stewart (1997) Nature 385:151-154.
Metz and Palumbi (1996) Mol. Biol. Evol. 13:397-406.
Nakashima et al. (1995) Proc. Natl. Acad. Sci. USA 92:5605-5609.
Nei (1987) in Molecular Evolutionary Genetics, Columbia University Press Pub., New York, NY, Table of Contents.
Nei and Hughes in Evolution at the Molecular Level, Sinauer Associates, Sunderland, MA, pp. 222-247 (1991).
Niewiesk and Bangham (1996) J. Mol. Evol. 42:452-458.
Novembre et al. (1997) Journal of Virology 71:4086-4091.
Parham and Ohta (1996) Science 272:67-74.
Patzwahl et al. (2000) J. Virology 75(3):1332-38.
Rumin et al. (199) J. Gen. Virology 80:3007.
Sharp (1997) Nature 385:111-112.
Swason & Vacquier (1995) Proc. Natl. Acad. Sci. USA 92:4957-4961.
Swanson and Vacquier (1998) Science 281:710-712.
Wettstein et al. (1996) Mol. Biol. Evol. 13:56-66.
Whitfield et al. (1993) Nature 364:713-715.
Wolinsky et al. (1996) Science 272:537-542.
Wu et al. (1997) J. Mol. Evol. 44:477-491.
Xu et al. (1997) Human Mol. Genetics 6(7):1057-62.
Yang (1998) Mol. Biol. Evol. 15:568-573.
Zhou and Li (1996) Mol. Biol. Evol. 13:780-783.
Messier Walter
Sikela James
Evolutionary Genomics LLC
Horlick Kenneth R.
Swanson & Bratschun LLC
LandOfFree
Methods to identify polynucleotide and polypeptide sequences... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods to identify polynucleotide and polypeptide sequences..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods to identify polynucleotide and polypeptide sequences... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3428605