Methods to deliver macromolecules to hair follicles

Details Methods to deliver macromolecules to hair follicles Methods to deliver macromolecules to hair follicles

1997-05-20

1999-06-22

Degen, Nancy

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

424 701, 514 2, 514 44, A61K 706, A61K 9127, A61K 3170, A61K 3800

Patent

active

059141263

ABSTRACT:
The invention provides methods to deliver macromolecules to hair follicles selectively using formulations of these macromolecules in liposomal separations.

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Hoffman, R.M. et al., "letter to the Editor: Liposomes can Specifically Target Entrapped Melanin to Hair Follicles in Histocultured Skin," In Vitro Cell. Dev. Biol. (Mar. 1993) 29A:192-194.
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Lieb, L.M. et al. "Topical Delivery Enhancement with Multilamellar Liposomes into Pilosebaceous Units: I. In Vitro Evaluation Using Fluorescent Techniques with the Hamster Ear Model," Journal of Investigative Dermatology (Jul. 1992) 99(1):108-113.
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