Methods to clear meningitis causing agents using antibodies...

Details Methods to clear meningitis causing agents using antibodies... Methods to clear meningitis causing agents using antibodies...

2000-01-24

2011-12-06

Duffy, Patricia A (Department: 1645)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Binds antigens of multiple bacterial species

C424S165100

Reexamination Certificate

active

08071102

ABSTRACT:
Novel vaccines include polypeptides that comprise regions corresponding to a chemokine and a hapten. The hapten can be an amino acid sequence corresponding to the Meningitis Related Homologous Antigenic Sequences (MRHAS) of bacterial and viral agents known to cause meningitis. Protective immunity in a host susceptible to meningitis can be induced by inoculating the host with immunogenic amount of such a vaccine.

REFERENCES:
patent: 6248329 (2001-06-01), Chandrashekar et al.
Feng et al (Infection and Immunity, 64(1):363-365, 1996).
Ellis, R.W. (Chapter 29 of “VACCINES” [Plotkin, S.A. et al. (eds) published by W. B. Saunders company (Philadelphia) in 1988, especially p. 571, 2nd full paragraph].
Fahey et al. (Clin. Exp. Immunol. 88: 1-5, 1991).
Daar et al. (PNAS 87: 6574-6578, 1990).
Haynes et al. (Science 271: 324-328, 1996).
Fox (Biotechnology 12: 128, 1994).
Sommerfelt et al. (J. Gen. Virol. 76: 1345-1352, 1995).
MSN Encarta Dictionary; definition of treatment and bacteremia.
Public Health agency of Canada Vaccine Preventable Diseases Rubella, p. 5-15, 2002.

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