Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation
Reexamination Certificate
2005-11-08
2005-11-08
Winakur, Eric F. (Department: 3736)
Surgery
Diagnostic testing
Detecting nuclear, electromagnetic, or ultrasonic radiation
C128S903000, C600S302000
Reexamination Certificate
active
06963770
ABSTRACT:
Methods of monitoring and evaluating the status of a tumor undergoing treatment includes monitoring in vivo at least one physiological parameter associated with a tumor in a subject undergoing treatment, transmitting data from an in situ located sensor to a receiver external of the subject, analyzing the transmitted data, repeating the monitoring and transmitting steps at sequential points in time and evaluating a treatment strategy. The method provides dynamic tracking of the monitored parameters over time. The method can also include identifying in a substantially real time manner when conditions are favorable for treatment and when conditions are unfavorable for treatment and can verify or quantify how much of a known drug dose or radiation dose was actually received at the tumor. The method can include remote transmission from a non-clinical site to allow oversight of the tumor's condition even during non-active treatment periods (in between active treatments). The disclosure also includes monitoring systems with in situ in vivo biocompatible sensors and telemetry based operations and related computer program products.
REFERENCES:
patent: 3229684 (1966-01-01), Nagumo et al.
patent: 3638640 (1972-02-01), Shaw
patent: 3972320 (1976-08-01), Kalman
patent: 4163380 (1979-08-01), Masoner
patent: 4326535 (1982-04-01), Steffel et al.
patent: 4361153 (1982-11-01), Slocum et al.
patent: 4397313 (1983-08-01), Vaguine
patent: 4397314 (1983-08-01), Vaguine
patent: 4416283 (1983-11-01), Slocum
patent: 4431004 (1984-02-01), Bessman et al.
patent: 4484076 (1984-11-01), Thomson
patent: 4494545 (1985-01-01), Slocum et al.
patent: 4519401 (1985-05-01), Ko et al.
patent: 4523279 (1985-06-01), Sperinde et al.
patent: 4541901 (1985-09-01), Parker et al.
patent: 4543953 (1985-10-01), Slocum et al.
patent: 4556063 (1985-12-01), Thompson et al.
patent: 4571292 (1986-02-01), Liu et al.
patent: 4571589 (1986-02-01), Slocum et al.
patent: 4575676 (1986-03-01), Palkuti
patent: 4625733 (1986-12-01), Säynäjäkangas
patent: 4638436 (1987-01-01), Badger et al.
patent: RE32361 (1987-02-01), Duggan
patent: 4651741 (1987-03-01), Passafaro
patent: 4655880 (1987-04-01), Liu
patent: 4678916 (1987-07-01), Thomson
patent: 4681111 (1987-07-01), Silvian
patent: 4703756 (1987-11-01), Gough et al.
patent: 4719919 (1988-01-01), Marchosky et al.
patent: 4750495 (1988-06-01), Moore et al.
patent: 4769547 (1988-09-01), Uber, III
patent: 4793825 (1988-12-01), Benjamin et al.
patent: 4796641 (1989-01-01), Mills et al.
patent: 4804847 (1989-02-01), Uber, III
patent: 4846191 (1989-07-01), Brockway et al.
patent: 4847617 (1989-07-01), Silvian
patent: 4900422 (1990-02-01), Bryan et al.
patent: 4919141 (1990-04-01), Zier et al.
patent: 4935345 (1990-06-01), Guilbeau et al.
patent: 4944299 (1990-07-01), Silvian
patent: 4958645 (1990-09-01), Cadell et al.
patent: 4961422 (1990-10-01), Marchosky et al.
patent: 4970391 (1990-11-01), Uber, III
patent: 4976266 (1990-12-01), Huffman et al.
patent: 4989601 (1991-02-01), Marchosky et al.
patent: 5008546 (1991-04-01), Mazziotta et al.
patent: 5012411 (1991-04-01), Policastro et al.
patent: 5098547 (1992-03-01), Bryan et al.
patent: 5109850 (1992-05-01), Blanco et al.
patent: 5117113 (1992-05-01), Thomson et al.
patent: 5117824 (1992-06-01), Keimel et al.
patent: 5126937 (1992-06-01), Yamaguchi et al.
patent: 5127404 (1992-07-01), Wyborny et al.
patent: 5137022 (1992-08-01), Henry
patent: 5159262 (1992-10-01), Rumbaugh et al.
patent: 5163380 (1992-11-01), Duffy et al.
patent: 5166073 (1992-11-01), Lefkowitz et al.
patent: 5186172 (1993-02-01), Fiddian-Green
patent: 5193538 (1993-03-01), Ekwall
patent: 5197466 (1993-03-01), Marchosky et al.
patent: 5205294 (1993-04-01), Flach et al.
patent: 5215887 (1993-06-01), Saito
patent: 5264843 (1993-11-01), Silvian
patent: 5309085 (1994-05-01), Sohn
patent: 5314450 (1994-05-01), Thompson
patent: 5324315 (1994-06-01), Grevious
patent: 5330634 (1994-07-01), Wong et al.
patent: 5354314 (1994-10-01), Hardy et al.
patent: 5354319 (1994-10-01), Wyborny et al.
patent: 5355880 (1994-10-01), Thomas et al.
patent: 5372133 (1994-12-01), Hogen et al.
patent: 5383909 (1995-01-01), Keimel
patent: 5425361 (1995-06-01), Fenzlein et al.
patent: 5431171 (1995-07-01), Harrison et al.
patent: 5444254 (1995-08-01), Thomson
patent: 5466246 (1995-11-01), Silvian
patent: 5470345 (1995-11-01), Hassler et al.
patent: 5476488 (1995-12-01), Morgan et al.
patent: 5480415 (1996-01-01), Cox et al.
patent: 5481262 (1996-01-01), Urbas et al.
patent: 5497772 (1996-03-01), Schulman et al.
patent: 5505828 (1996-04-01), Wong et al.
patent: 5507786 (1996-04-01), Morgan et al.
patent: 5517313 (1996-05-01), Colvin, Jr.
patent: 5535752 (1996-07-01), Halperin et al.
patent: 5538005 (1996-07-01), Harrison et al.
patent: 5545187 (1996-08-01), Bergstrom et al.
patent: 5549113 (1996-08-01), Halleck et al.
patent: 5549654 (1996-08-01), Powell
patent: 5556421 (1996-09-01), Prutchi et al.
patent: 5562713 (1996-10-01), Silvian
patent: 5564434 (1996-10-01), Halperin et al.
patent: 5571148 (1996-11-01), Loeb et al.
patent: 5591217 (1997-01-01), Barreras
patent: 5593430 (1997-01-01), Renger
patent: 5596199 (1997-01-01), McNulty et al.
patent: 5620472 (1997-04-01), Rahbari
patent: 5620475 (1997-04-01), Magnusson
patent: 5620479 (1997-04-01), Diederich
patent: 5626630 (1997-05-01), Markowitz et al.
patent: 5626862 (1997-05-01), Brem et al.
patent: 5628324 (1997-05-01), Sarbach
patent: 5630413 (1997-05-01), Thomas et al.
patent: 5720771 (1998-02-01), Snell
patent: 5732704 (1998-03-01), Thurston et al.
patent: 5744804 (1998-04-01), Meijer et al.
patent: 5744805 (1998-04-01), Raylman et al.
patent: 5759199 (1998-06-01), Snell et al.
patent: 5791344 (1998-08-01), Schulman et al.
patent: 5814089 (1998-09-01), Stokes et al.
patent: 5833603 (1998-11-01), Kovacs et al.
patent: 5879375 (1999-03-01), Larson et al.
patent: 5891179 (1999-04-01), Er et al.
patent: 5918110 (1999-06-01), Abraham-Fuchs et al.
patent: 5932879 (1999-08-01), Raylman et al.
patent: 6047214 (2000-04-01), Mueller et al.
patent: 6076009 (2000-06-01), Raylman et al.
patent: 6172368 (2001-01-01), Tarr et al.
patent: 6239724 (2001-05-01), Doron et al.
patent: 6240312 (2001-05-01), Alfano et al.
patent: 6304766 (2001-10-01), Colvin, Jr.
patent: 6431175 (2002-08-01), Penner et al.
patent: 6475170 (2002-11-01), Doron et al.
patent: 6486588 (2002-11-01), Doron et al.
patent: 6614025 (2003-09-01), Thomson et al.
patent: 6650930 (2003-11-01), Ding
patent: 6699186 (2004-03-01), Wolinsky et al.
patent: 6764446 (2004-07-01), Wolinsky et al.
patent: 3219558 (1983-01-01), None
patent: 33 32 075 (1984-03-01), None
patent: 4341903 (1995-06-01), None
patent: 0 420 177 (1991-03-01), None
patent: 471 957 (1992-02-01), None
patent: 0537761 (1993-04-01), None
patent: 0245073 (1993-12-01), None
patent: 0386218 (1996-01-01), None
patent: 2 263 196 (1993-07-01), None
patent: WO 95/17809 (1995-07-01), None
patent: WO 97/33513 (1997-09-01), None
patent: WO 98/02209 (1998-01-01), None
patent: PCT/US98/05965 (1998-02-01), None
patent: WO 98/43701 (1998-10-01), None
patent: WO 98/58250 (1998-12-01), None
patent: WO 00/29096 (2000-05-01), None
patent: WO 00/40299 (2000-07-01), None
patent: WO 02/09775 (2002-02-01), None
patent: WO 02/100485 (2002-12-01), None
Alecu et al.,Dose perturbations due to in vivo dosimetry with diodesRadiotherapy and Oncology, pp. 289-291, vol. 42, (1997).
Jornet et al.,Calibration of semiconductor detectors for dose assessment in total body irradiation; Radiotherapy and Oncology, pp. 247-251, vol. 38, (1996).
Loncol et al., “Entrance and exit dose measurements with semiconductors and thermoluminescent dosemeters: a comparison of methods and in vivo results”, Radiotherapy and Oncology, pp. 179-187, vol. 41, (1996).
National Aeronautics and Space Administration,Extravehicular Activity Radiation Monitoring(EVARM), Fact Sheet FS 2001-11-192-MSFC, abstract review, Oct. 2001.
Reece M.H. et al.,Semiconductor Mosfet Dosimetry, Health Physics Society annual Meeting, pp. 1-14, 1988.
Shortt, Dr. Ken et al.,A New Direct Reading
Hall Lester C.
Mueller Jeffrey
Nagle H. Troy
Scarantino Charles W.
Myers Bigel & Sibley Sajovec, PA
North Carolina State University
Sicel Techonologies, Inc.
Winakur Eric F.
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