Adhesive bonding and miscellaneous chemical manufacture – Methods – Surface bonding and/or assembly therefor
Patent
1997-06-20
2000-01-18
Gallagher, John J.
Adhesive bonding and miscellaneous chemical manufacture
Methods
Surface bonding and/or assembly therefor
156336, 206568, 427 21, 427323, 428420, 4284766, 523118, C09J 504
Patent
active
060154748
ABSTRACT:
The present invention concerns novel methods for enhancing the mechanical performance of tissue adhesives and sealants which comprises employing a primer molecule in association with a tissue adhesive or sealant, wherein the primer molecule serves to enhance the strength of the interface between the tissue and the adhesive matrix. The primer molecules described herein function to interact with collagen present in the tissue, thereby altering its characteristics to make it more amenable to bonding with the adhesive matrix. Primer molecules may be applied to the tissue independently from the tissue adhesive or sealant or may be mixed with the tissue adhesive or sealant prior to application to the tissue.
REFERENCES:
patent: 4364473 (1982-12-01), Bogaert
patent: 4382792 (1983-05-01), Smith et al.
patent: 4593054 (1986-06-01), Asmuvven et al.
patent: 4766005 (1988-08-01), Montgomery et al.
patent: 4913939 (1990-04-01), Montgomery
patent: 5015677 (1991-05-01), Benedict et al.
patent: 5733868 (1998-03-01), Peterson et al.
Chuck, R.S., et al., "Dye-Enhanced Laser Tissue Welding", Lasers in Surgery and Medicine, 9:471-477 (1989).
Oz, M.C., et al., "Indocyanine Green Dye-Enhanced Welding with Diode Laser", Surgical Forum, vol. XL:316-319 (Oct. 15-20, 1989).
Schober, R., et al., "Laser-Induced Alteration of Collagen Substructure Allows Microsurgical Tissue Welding", Science, vol. 232:1421-1422 (1986).
Wider, T.M., et al., "Skin Closure with Dye-Enhanced Laser Welding and Fibrinogen", Plastic and Reconstructive Surgery, vol. 88 (6):1018-1025 (Dec. 1991).
Oz, M.C., et al., "Tissue soldering by use of indocyanine green dye-enhanced fibrinogen with the near infrared diode laser", Journal of Vascular Surgery, vol. 11(5):718-725 (May 1990).
Gallagher John J.
Protein Polymer Technologies
Trecartin Richard F.
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