Methods of using polypeptides encoding transcriptional activator

Details Methods of using polypeptides encoding transcriptional activator Methods of using polypeptides encoding transcriptional activator

1998-02-18

1999-01-26

Degen, Nancy

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 4, 435 6, 435 691, 530350, 536 231, 536 245, G01N 3353, A61K 3816, C07H 2104, C12Q 168

Patent

active

058637370

ABSTRACT:
The invention provides a purified polypeptide having substantially the same amino acid sequence and activity as the protein having the amino acid sequence of FIG. 1, or a characteristic fragment thereof. The polypeptide is a transcriptional activator. Nucleic acids encoding the polypeptide and uses are also provided.

REFERENCES:
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Moreau-Gachelin et al., "Spi-1 is a Putative Oncogene in Virally Induced Murine Erythroleukaemias," Nature 331:277-280 (1988).
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Serfling et al., "Ubiquitous and Lymphocyte-specific Factors are Involved in the Induction of the Mouse Interleukin 2 Gene in T Lymphocytes," EMBO Journal 8:465-473 (1989).
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