Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lipoproteins – e.g. – egg yolk proteins – cylomicrons – etc.
Reexamination Certificate
2005-10-11
2005-10-11
Weber, Jon (Department: 1653)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lipoproteins, e.g., egg yolk proteins, cylomicrons, etc.
C514S012200, C530S350000
Reexamination Certificate
active
06953840
ABSTRACT:
The invention provides methods and compositions for treating disorders using non-human animal Apolipoprotein A-I (ApoA-I) protein. The invention provides methods and compositions for treating disorders in animals, including humans, associated with dyslipidemia, including hyperlipidemia, hyperlipoproteinemia, hypertriglyceridemia, hypercholesterolemia, HDL deficiency, ApoA-I deficiency, cardiovascular disease, atherosclerosis, restenosis, and other disorders such as septic shock and viral infections.
REFERENCES:
patent: 6037323 (2000-03-01), Dasseux et al.
Schakelford et al., Snthesis and Secretion of Apolipoprotein A1 by chick Breast Muscle, Jun. 10, 1983, The Journal of Biological Chemistry, vol. 258, No. 11, pp. 7175-7180.
Altschul et al., “Basic Local Alignment Search Tool,” 1990,J Mol Biol215(3):403-410.
Altschul et al., “Gapped BLAST and PSI-BLAST: A New Generation of Protein Database Search programs,” 1997,Nucleic Acids Res25:3389-3402.
Babin, P.J., et al., “Both Apolipoprotein E and A-1 Genes are Present in a Nonmammalian Vertebrate and are Highly Expressed During Embryonic Development,” (1997),Proc. Natl. Acad. Sci. U.S.A., 94(16), pp. 8622-8627.
Banerjee, D., et al., “Biosynthesis of High Density Lipoprotein by Chicken Liver: Intracellular Transport and Proteolytic Processing of Nascent Apolipoprotein A-1,”J Cell Biol., (1985), 101(4), pp. 1219-1226.
Beaubatie et al., “Isolation and Characterization of the Major Plasma Apolipoproteins, A-1 and B, in the European Badger,Meles meles,” 1986,J Lipid Res27:140-149.
Bhattacharyya, N., et al., “Isolation, Characterization and Sequencing of the Chicken Apolipoprotein A1 Encoding Gene,” (1991),Gene, 104(2), pp. 163-168.
Blaton et al., “Characterization of Babbon Plasma High-Density Lipoproteins and of Their Major Apoproteins,” 1977,Biochemistry16:2157-2163.
Brouilette et al., “Structural Models of Human Apolipoprotein A-1: A Critical Analysis and Review,” 2001,Biochim Biophys Acta1531:4-46.
Byrnes, L., et al., “Chicken Apolipoprotein A-I:cDNA Sequence, Tissue Expression and Evolution,” (1987),Biochem. Biophys. res. Commun., 148(1), pp. 485-492.
Chen and Albers, “Interspecies Activation of Lecithin-Cholesterol Acyltransferase by Apolipoprotein A-I Isolated from the Plasma of Humans, Horses, Sheep, Goats and Rabbits,” (1983),Biochim. Biophys. Acta, 753(1), pp. 40-46.
Collet, X., et al., “Evolution of Mammalian Apolipoprotein A-I and Conservation of Antigenicity: Correlation with Primary and Secondary Structure,” (1997),J Lipid Res., 38(4), pp. 634-644.
Concha, M.I., et al., “Local Expression of Apolipoprotein A-I Gene and a Possible Role for HDL in Primary Defence in the Carp Skin,” (2003),Fish Shellfish Immunol., 14(3), pp. 259-273.
Ferrari, S., et al., “The Complete Sequence of Chick Apolipoprotein AI mRNA and Its Expression in the Developing Chick,” (1987),Gene, 60(1), pp. 39-46.
Frank, P.G., et al., “Apolipoprotein A-I: Structure-Function Relationships,” (2000),J Lipid Res., 41(6), pp. 853-872.
GenBank Accession No. NM_000039.
GenBank Accession No. A56858.
GenBank Accession No. JT0672.
GenBank Accession No. A61448.
GenBank Accession No. CAA30377.
GenBank Accession No. X07496.1.
GenBank Accession No. S31394.
GenBank Accession No. LPCHA1.
Goulinet, S., et al., “Plasma Lipoproteins in the Golden Syrian Hamster (Mesocricetus Auratus): Heterogeneity of apoB-and apoAI-Containing Particle,” (1993),J Lipid Res., 34(6), pp. 943-959.
Gu, Z.W., et al., “Primary Structure of Beijing Duck Apolipoprotein A-1,” (1993),J Protein Chem., 12(5), pp. 585-591.
Jackson, R.L., et al., “Isolation and Characterization of the Major Apolipoprotein From Chicken High Density Lipoproteins,” (1976),Biochim. Biophys. Acta., 420(2), pp. 342-349.
Januzzi, J.L., et al., “Characterization of the Mouse Apolipoprotein Apoa-1/Apoc-3 Gene Locus: Genomic, mRNA, and Protein Sequences with Comparisons to Other Species,”Genomics, 14(4), pp. 1081-1088.
Kelley, J.L., et al. “Lipid Transport in the Avian Species. Part I Isolation and Characterization of Apolipoproteins and Major Lipoprotein Density Classes of Male Turkey Serum,” (1976),Atheroscler., 24(1-2), pp. 155-175.
Kelley, J.L., et al., “Lipid Transport in the Avian Species. Part 2. Isolation and Characterization of Lipoprotein A and Lipoprotein B, two major Lipoprotein Families of the Male Turkey Serum Lipoprotein System,” (1976),Atheroscler., 24(1-2), pp. 177-187.
Kiss, R.S., et al., “Amphipathic Alpha-Helix Bundle Organization of the Lipid-Free chicken Apolipoprotein A-I,” (1999),Biochem., 38(14), pp. 4327-4334.
Lamon-Fava, S., et al., “Evolutionary Distinct Mechanisms Regulate Apolipoprotein-A-I Gene expression: Differences Between Avian and Mammalian apoA-I Gene Transcription Control Regions,” (1992),J Lipid Res., 33(6), pp. 831-842.
Li, W.H., et al., “The Apolipoprotein Multigene Family: Biosynthesis, Structure, Structure-Function Relationships, and Evolution,”, (1988),J Lipid Res., 29(3), pp. 245-271.
Liu, A.C., et al., “Human Apolipoprotein A-I Prevents Atherosclerosis Associated with Apolipoprotein [a] in Transgenic Mice,” (1994),J Lipid Res., 35, pp. 2263-2267.
Luo, C.C., et al., “Structure and Expression of Dog Apolipoprotein A-I, E, and C-I mRNAs: Implications for the Evolution and Functional Constraints of Apolipoprotein Structure,” (1989),J Lipid Res., 30, pp. 1735-1746.
Mezdour, H., et al., “Exogenous Supply of artificial Lipoproteins does Not Decrease Susceptibility to Atherosclerosis in Cholesterol-fed Rabbits,” (1995),Atheroscler., 113, pp. 237-246.
Rajavashisth, T.B., et al., “Structure, Evolution, and Regulation of Chicken Apolipoprotein A-I,” (1987),J Biol. Chem, 262(15), pp. 7058-7065.
Rubin, E.M., et al., “Inhibition of Early Atherogenesis in Transgenic Mice by Human Apolipoprotein AI,” (1991),Nature, 353, pp. 265-267.
Segrest, J.P., et al., “Structure and Function of Apolipoprotein A-I and High-Density Lipoprotein,” (2000),Curr. Opin. Lipidol., 11(2), pp. 105-115.
Shackleford, J.E., et al., “Synthesis and Secretion of Apolipoprotein A, by Chick Breast Muscle,” (1983),J Biol. Chem., 258(11), pp. 7175-7180.
Smith et al., “The Plasma Lipoproteins: Structure and Metabolism,” 1978,Ann Rev Biochem47:751-777.
Sparrow et al., “Plasma Lipid Transport in the Preruminant Calf, Bos spp: Primary Structure of Bovine Apolipoprotein A-I,” 1992,Biochim Biophys Acta1123:145-150.
Sparrow, D.A., et al., “Plasma Lipid Transport in the Hedgehog: Partial Characterization of Structure and Function of Apolipoprotein A-I,” (1995),J Lipid Res., 36(3), pp. 485-495.
Swaney, 1980,Biochim Biophys Acta617:489-502.
Trieu et al., “Sequences and Expression of the Porcine Apolipoprotein A-I and C-III mRNAs,” 1993,Gene123(2):173-179.
Trieu et al., “Sequebce of the Porcine ApoA-I Gene,” 1993,Gene134 (2):267-270.
Weiler-Guttler, H., et al., “Synthesis of Apolipoprotein A-I in Pig Brain Microvascular Endothelial Cells,” (1990),J Neurochem., 54(2), pp. 444-450.
Yang, C.Y., et al., “The Primary Structure of Apolipoprotein A-I from Rabbit High-Density Lipoprotein,” (1986),Eur. J Biochem., 160(2), pp. 427-431.
Yang, et al., “The Complete Amino Acid sequence of Proapolipoprotein A-I of Chicken High Density Lipoproteins,” (1987),FEBS Lett., 224(2), pp. 261-266.
Yu, F.G., et al., “Characterization of Lipoprotein Secreted by Cultured Eel Hepatocytes and Its Comparison with Serum Lipoproteins,” (1991),Cell Struct Funct., 16(4), pp. 347-355.
Dasseux Jean-Louis
Lalwani Narendra D.
Zhu Lingyu
Esperion Therapeutics, Inc.
Jones Day
Mondesi Robert
Weber Jon
LandOfFree
Methods of using non-human animal Apolipoprotein A-I protein does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods of using non-human animal Apolipoprotein A-I protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of using non-human animal Apolipoprotein A-I protein will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3476834