Methods of using G-CSF analog compositions

Details Methods of using G-CSF analog compositions Methods of using G-CSF analog compositions

2004-08-03

2008-05-13

Mertz, Prema (Department: 1646)

Drug, bio-affecting and body treating compositions

Lymphokine

C514S002600, C514S008100, C514S012200

Reexamination Certificate

active

07371370

ABSTRACT:
The present invention relates to granulocyte colony stimulating factor (“G-CSF”) polypeptide analog compositions. The concept detailed herein provides methods for screening G-CSF analogs, designed with one or more substitutions to amino acids, and selecting analogs for use as G-CSF replacements or antagonists, and may be generalizable beyond G-CSF analogs as well. In addition, pharmaceutical compositions and methods of use are provided for analogs so selected.

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