Methods of using emu oil and active fractions thereof as an inse

Details Methods of using emu oil and active fractions thereof as an inse Methods of using emu oil and active fractions thereof as an inse

1996-11-18

1997-10-14

Pak, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514546, 514549, 514558, 514560, 514919, 424522, 424DIG10, A01N 3702, A01N 3706, A01N 6300, A61K 3512

Patent

active

056773382

ABSTRACT:
This invention provides a method for repelling biting insects such as mosquitoes by topically applying to the skin of a subject fractions of emu oil obtained by flash chromatography. Also provided are methods for repelling biting insects by topically applying diluted fractions of emu oil. The invention also provides a compound useful in repelling biting insects having the NMR spectrum of FIG. 3, that is ultra violet light sensitive and is reactive to vanillin/sulfuric acid. Also provided are compounds useful in repelling biting insects having the NMR spectrum of FIG. 4, that is not ultra violet light sensitive and is not reactive to vanillin/sulfuric acid.

REFERENCES:
patent: 4293422 (1981-10-01), Still
patent: 5208209 (1993-05-01), Otsuji et al.
patent: 5346922 (1994-09-01), Bedlock et al.
patent: 5431924 (1995-07-01), Ghosh et al.
patent: 5472713 (1995-12-01), Fein et al.
Wantanabe et al., "Rotundial, a new natural mosquito repellant from the leaves of Vitex rotundifolia"Biotech Biochem. (1995) 59(10):1979-1980.
Wantanabe et al., "New mosquito repellant from Eucalyptus camaldulensis" J. Agric. Food Chem. (1993) 41:2164-2166.
Sharma et al., "Mosquito repellant action of Neem (Azadirachta indica) oil" J. Am. Mosquito Control Assn. (1993) 9(3):359-360.
Still et al., "Rapid chromatographic technique for preparative separations with moderate resolution" J. Organic Chem. (1978) 43: 2923-2925.
PROMT Database, Accession No. 96: 342230 (1996).

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