Methods of using emu oil and active fractions thereof as an inse

Details Methods of using emu oil and active fractions thereof as an inse Methods of using emu oil and active fractions thereof as an inse

1997-04-04

1998-09-01

Pak, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514549, 514552, 514557, 514558, 514919, 424522, 424520, 424DIG10, A01N 3702, A01N 3706, A61K 3512

Patent

active

058011960

ABSTRACT:
This invention provides a method for repelling biting insects such as mosquitoes by topically applying to the skin of a subject fractions of emu oil obtained by flash chromatography. Also provided are methods for repelling biting insects by topically applying diluted fractions of emu oil. The invention also provides a compound useful in repelling biting insects having the NMR spectrum of FIG. 3, that is ultra violet light sensitive and is reactive to vanillin/sulfuric acid. Also provided are compounds useful in repelling biting insects having the NMR spectrum of FIG. 4, that is not ultra violet light sensitive and is not reactive to vanillin/sulfuric acid.

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Wantanabe et al., "Rotundial, a new natural mosquito repellent from the leaves of Vitex rotundifolia" Biotech Biochem. (1995) 59(10):1979-1980.
Wantanabe et al., "New mosquito repellent from Eucalyptus camaldulensis" J. Agric. Food Chem. (1993) 41:2164-2166.
Sharma et al., "Mosquito repellent action of Neem `Azadirachta indica` oil" J. Am. Mosquito Control Assn. (1993) 9(3):359-360.
PROMT Database Accession No. 96:342230 (Jul. 1, 1996) "Emu oil takes the bite out of bugs" PR NewsWire, Miami, Florida.
Still et al., "Rapid chromatographic technique for preparative separations with moderate resolution" J. Org. Chem. (1978) 43:2923-2925.

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