Methods of using dynorphins as ligands for XOR1 receptor

Details Methods of using dynorphins as ligands for XOR1 receptor Methods of using dynorphins as ligands for XOR1 receptor

1997-06-24

1999-02-02

Teng, Sally P.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 6, 435 691, 530350, 536 235, C12Q 100, C12N 1512, C07K 14705

Patent

active

058663460

ABSTRACT:
Orphan receptor expressed in Xenopus oocytes. The coupling of the receptor to a G protein-activated K.sup.+ channel was used as a functional essay in oocytcs. Endogenous opioid peptides dynorphins were found to activate the K.sup.+ channel by stimulating the orphan receptor.

REFERENCES:
Chen et al., FEBS Letters, 347, 279-283, Jun. 1994.
Grudi et al., Proc. Natl. Acad. Sci, 90, 11429-11432, Dec. 1993.
Lachowicz et al. J. Neurochem 64:34-40, (1995).
Wick et al., Molecular Brain Research 27:37-44, (1994).
Bunzow et al., FEBS Lett. 347:284-288, (1994).
Fubuda et al., FEBS Lett. 343:42-46, (1994).
Raynor et al., Molec. Pharmac. 45:330-334, (1993).
Walker et al., Life Sci. 31:1821-1824, (1992).

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