Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1994-03-04
1995-07-18
Killos, Paul J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514120, 514143, 514557, 514690, 514709, 514738, A01N 5726
Patent
active
054341442
ABSTRACT:
The subject invention relates to methods of regulating skin wrinkles and/or atrophy in mammalian skin comprising topically applying to the skin of a mammal in need of treatment a composition comprising a safe and effective amount of a cyclic polyanionic polyol derivative having the structure: ##STR1## wherein n is an integer from 1 to 3; and each X is, independently, selected from the group consisting of OSO.sub.3.sup.-, OPO.sub.3.sup..dbd., SO.sub.3.sup.--, PO.sub.3.sup..dbd., CO.sub.2.sup.--, and OH; with at least 3 X's being other than OH.
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Morel, N. et al., J. Cell. Physiol. (1989) 141 (3) 653-9.
Rosenbach, T. et al., Arch. Dermatol. Res. (1993) 285 (7) 393-6.
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Lei, Xuejun, "Extraction of Phytic Acid and its Application in Ordinary Chemical Engineering", Riyong Huaxue Gongye, vol. 5, pp. 223-224, 1989.
Gardlik John M.
Kasting Gerald B.
Graff IV Milton B.
Howell John M.
Killos Paul J.
Suter David L.
The Procter & Gamble & Company
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