Methods of using compositions having antithrombotic and anti-blo

Details Methods of using compositions having antithrombotic and anti-blo Methods of using compositions having antithrombotic and anti-blo

1983-05-16

1985-08-27

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514302, 514404, 514822, A61K 31415, A61K 31435

Patent

active

045378940

ABSTRACT:
This invention relates to a therapeutic composition comprising, as active ingredient, a combination of a pyridine derivative having an anti-blood-platelet-aggregation activity and of sulfinpyrazone.
Said composition has outstanding anti-blood-platelet-aggregating and antithrombotic properties, both components of the active ingredient functioning according to a synergistic effect.

REFERENCES:
patent: 4075340 (1978-02-01), Maffrand
patent: 4097482 (1978-06-01), Amselem
Goodman & Gilman-The Pharmacological Basis of Therapeutics, 5th Ed., 1975, pp. 863-864 & 1365-1368.
Packman et al., J. Exp. Med., vol. 126, pp. 171-188 (1967).
Peleirac et al., "Essai Therapeutique", M.M. No. 205, 12/79, pp. 55-61.

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