Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Reexamination Certificate
2007-09-18
2007-09-18
Kam, Chih-Min (Department: 1656)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
C424S236100, C424S009100, C514S002600, C514S012200, C530S350000, C435S252700
Reexamination Certificate
active
11028600
ABSTRACT:
The present invention uses pharmaceutical preparations ofBotulinumtoxin to induce neurogenic atrophy to alter muscle volume and subsequently, facial contour. Reduction in lip volume is accomplished using the disclosed methods thereby producing a favorable effect on a hypervolemic lip deformity. In other embodiments of the invention, the methods disclosed herein may be used to shrink muscle bulk and contour, especially in the face. In one embodiment, treating excessive muscle bulk below the eyelids can cause a smoothing of the lower lid and cheek contour producing a favorable improvement in appearance. Such an application is in distinct contrast to rhytide (wrinkle reduction) as the injected region does not contain wrinkles or any other form of dynamic line, merely excessive tissue bulk.
REFERENCES:
patent: 2280565 (2001-02-01), None
patent: WO 2004/060384 (2004-07-01), None
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Mataraso, Seth L. et al., “Treatment Guidelines for Botulinum Toxin Type A for the Periocular Region and a Report on Partial Upper Lip Ptosis Following Injections to the Lateral Canthal Rhytids”, Plastic and Recostructive Surgery, Jul. 2001, XP008046805, vol. 108 (1), 208-217.
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