Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2002-07-23
2008-09-30
Nguyen, Bao-Thuy L. (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007920, C435S007930, C435S007950, C435S069100, C436S536000, C436S538000, C436S539000, C530S402000, C530S403000, C530S412000, C530S413000
Reexamination Certificate
active
07429458
ABSTRACT:
Bioelastomers are disclosed for use in methods of binding compounds including immunoassay methods, in biosensors and methods or regenerating biosensors, and in methods for targeting the delivery of a compound to a particular location within an animal subjects. In general, the bioelastomer is conjugated to a binding compound, which is in turn used to bind a compound of interest. For targeted compound delivery, the bioelastomer is conjugated to the compound to be delivered.
REFERENCES:
patent: 4474851 (1984-10-01), Urry
patent: 4749647 (1988-06-01), Thomas et al.
patent: 4752638 (1988-06-01), Nowinski et al.
patent: 5288514 (1994-02-01), Ellman
patent: 5445934 (1995-08-01), Fodor et al.
patent: 5624711 (1997-04-01), Sundberg et al.
patent: 5702717 (1997-12-01), Cha et al.
patent: 5816259 (1998-10-01), Rose
patent: 5900405 (1999-05-01), Urry
patent: 5998588 (1999-12-01), Hoffman et al.
patent: 6004782 (1999-12-01), Daniell et al.
patent: 6329209 (2001-12-01), Wagner et al.
Monji, et al., A novel immunoassay system and bioseparation process based on thermal phase separating polymers,Applied Biochemistry&Biotechnology, vol. 14, pp. 107-120 (1987).
Wu, Xue Shen, et al., Conjugation of phosphatidylethanolamine to poly(N-isopropylacrylamide) for potential use in liposomal drug delivery systems,Polymer, vol. 33, No. 21, pp. 4659-4662 (1992).
Nguyen, A.L., et al., Synthesis and Applications of Water-Soluble Reactive Polymers for Purification and Immobilization of Biomolecules,Biotechnology and Bioengineering, vol. 34, pp. 1186-1190 (Nov. 1989).
Umeno, Daisuke, et al., Temperature-Induced Precipitation of Specific DNA Fragments Using DNA-Poly(N-isopropylacrylamide) Conjugate,Chemistry Letters, pp. 381-382 (1999).
Umeno, Daisuke, et al., Single stranded DNA-poly(N-isopropylacrylamide) conjugate for affinity precipitation separation of oligonucleotides,Chem. Commun., pp. 1433-1434 (1998).
Takei, Yoshiyuki, et al., Temperature-Responsive Bioconjugates. 3. Antibody-Poly(N-isopropylacrylamide) Conjugates for Temperature-Modulated Precipitations and Affinity Bioseparations,Bioconjugate Chem, vol. 5, pp. 577-582 (1994).
Takei, Yoshiyuki, et al., Temperature-Responsive Bioconjugates. 1. Synthesis of Temperature-Responsive Oligomers with Reactive End Groups and Their Coupling to Biomolecules,Bioconjugate Chem, vol. 4, pp. 42-46 (1993).
Takei, Yoshiyuki, et al., Temperature-Responsive Bioconjugates. 2. Molecular Design for Temperature-Modulated Bioseparations,Bioconjugate Chem., vol. 4, pp. 341-346 (1993).
Stayton, patric S., et al., Control of protein-ligand recognition using a stimuli-responsive polymer,Nature, vol. 378, pp. 472, 474 (Nov. 30, 1995).
Monjui, Nobuo, et al, A Novel Immunoassay System and Bioseparation Process Based on Thermal Phase Separating Polymers,Applied Biochemistry and Biotechnology, vol. 14, pp. 107-120 (1987).
Monji, Nobuo, et al., Application of a Thermally-Reversible Polymer-Antibody Conjugate in a Novel Membrane-Based Immunoassay,Biochemical and Biophysical Research Communications, vol. 172, No. 2, pp. 652-660 (Oct. 30, 1990).
Maeda, Mizuo, et al., Modification of DNA with poly(N-isopropylacrylamide) for thermally induced affinity separation,Reactive Polymers, vol. 21, pp. 27-35 (1993).
Chen, Guohua, et al., A new temperature- and pH-responsive copolymer for possible use in protein conjugation,Macromol. Chem. Phys., vol. 196, pp. 1251-1259 (1995).
Galaev, I.Yu, et al., Affinity Thermoprecipitations: Contribution of the Efficiency of Ligand-Protein Interaction and Access of the Ligand,Biotechnology and Bioengineering, vol. 41, pp. 1101-1106 (1993).
Chen, Guohua, et al., Preparation and Properties of Thermoreversible, Phase-Separating Enzyme-Oligo(N-isopropylacrylamide) Conjugates,Bioconjugate Chem., vol. 4, pp. 509-514 (1993).
Chen, Jing Ping, et al., Polymer-protein conjugates; II. Affinity precipitation separation of human immunogammaglobulin by a poly(N-isopropylacrylamide)-protein A conjugate,Biomaterials, vol. 11, pp. 631-634 (Nov. 1990).
International Search Report dated Aug. 15, 2000; International Application No. PCT/US00/05780.
Abstract, Woods, et al., Protein Nanopatterning on a Gold/Aluminum Nanoarray,Vacuum, Thin Films, Surface/Interfaces and Processes, 46th International Symposium, p. 156 (Oct. 25-29, 1999).
Duke University
Myers Bigel Sibley & Sajovec P.A.
Nguyen Bao-Thuy L.
LandOfFree
Methods of using bioelastomers does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods of using bioelastomers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of using bioelastomers will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3982277