Methods of using aminothiols to promote hematopoietic progenitor

Details Methods of using aminothiols to promote hematopoietic progenitor Methods of using aminothiols to promote hematopoietic progenitor

1995-02-17

1998-12-08

Cook, Rebecca

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514119, 514613, 514646, 514665, A61K 3166

Patent

active

058469583

ABSTRACT:
The present invention relates to methods of stimulating the growth of hematopoietic progenitor cells. In particular, it relates to the use of thiols and related compounds in stimulating the growth of hematopoietic progenitor cells in vitro and in vivo. Furthermore, the present invention relates to methods of using these compounds for the treatment of marrow failure states and immunodeficient conditions, including but not limited to myelodysplastic syndromes and acquired immunodeficiency syndrome.

REFERENCES:
Toohey, Proc. Nat. Acad. Sci. USA., vol. 72, No. 1, pp. 73-77, Jan. 1975.
CA110:71915, 1989.
Patchen et al, Seminars on Oncology, vol. 21, No. 5, Suppl 11, (Oct.) 1994, p. 26-32.

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