Methods of using agents that modulate bone formation and...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...

Reexamination Certificate

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C435S006120, C435S007100, C435S320100, C435S455000, C536S023100, C536S023200, C536S024100

Reexamination Certificate

active

06916603

ABSTRACT:
The present invention is based on the discovery that overexpression of ΔFosB leads to bone formation and that ΔFosB expression inhibits adipogenesis. The present invention provides methods of identifying agents that modulate bone formation and adipogenesis. Moreover, the present invention provides methods for identifying genes that are modulated by ΔFosB and that modulates ΔFosB, osteogenesis, and adipogenesis.

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