Methods of use of uncoated gel particles

Details Methods of use of uncoated gel particles Methods of use of uncoated gel particles

1994-04-15

1997-07-29

Pak, John

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424422, 424423, 435174, 435177, 435243, 435382, 514866, 514885, 514907, 514953, C12N 1104, A61K 952

Patent

active

056519800

ABSTRACT:
The invention covers a method of implanting a living donor cell into a host animal without inflammatory response or rejection of the donor cell by the host animal, by obtaining an uncoated particle of a biocompatible, temperature-independent gel that encapsulates the living donor cell, wherein the uncoated particle provides a molecular weight cutoff that prevents host animal immune cells from entering the particle, yet does not have to prevent entry of host animal IgG and complement into the particle, and implanting the uncoated particle into the host animal.

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