Methods of use of phthalocyanines to inactivate blood borne para

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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A61K 31555

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059122412

ABSTRACT:
This invention relates to a method for inactivating parasites in blood cell-containing compositions by incubating a mixture of the blood cell-containing composition, a phthalocyanine dye and a quencher and optionally irradiating this mixture with red light. This invention further relates to a method of sterilizing blood cell-containing compositions which contain lipid enveloped viruses and blood borne parasites.

REFERENCES:
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R. Buhl et al., "Systemic Glutathione Deficiency in Symptom-free HIV-Seropositive Individuals", The Lancet, Dec. 2, 1989, pp. 1294-1297.
M. Roederer et al., "N-Acetylcysteine Inhibits Latent HIV Expression in Chronically Infected Cells", AIDS Research and Human Retroviruses, 1991, 7(6):563-567.
Ben Hur et al 123:CA: 208776y 1995.

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