Methods of use of a ductal carcinoma antigen

Details Methods of use of a ductal carcinoma antigen Methods of use of a ductal carcinoma antigen

1997-11-26

1999-02-16

Feisee, Lila

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 723, 435344, 4353441, 53038885, G01N 3353, C07K 1620, C12N 520

Patent

active

058719369

ABSTRACT:
Monoclonal antibodies to adenocarcinoma cells, and, in particular, breast carcinoma cells, are produced by a hybridoma formed by fusing mouse lymphocytes and mouse myeloma cells. The monoclonal antibodies are capable of shrinking solid tumors associated with human breast. The monoclonal antibodies identify an antigen associated with carcinomas of ductal lineage. The monoclonal antibodies, specifically, F36/22 monoclonal antibodies, can be used diagnostically and therapeutically.

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