Methods of use and compositions of (R)-isoflurane and (R)-desflu

Details Methods of use and compositions of (R)-isoflurane and (R)-desflu Methods of use and compositions of (R)-isoflurane and (R)-desflu

1990-11-29

1992-05-19

Pace, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

424435, 514816, 568684, C07C 4144, C07C 43192

Patent

active

051147149

ABSTRACT:
Disclosed is a method of inducing and maintaining anesthesia while avoiding concomitant liability of adverse effects comprising administering by inhalation to a warm blooded animal in need of anesthesia an amount sufficient to induce and maintain anesthesia but insufficient to cause said adverse effects, of (R)-isoflurane or (R)-desflurane, substantially free of its (S)-stereoisomer. Also disclosed are novel compositions of these compounds for use in the above disclosed method.

REFERENCES:
patent: 3469011 (1970-10-01), Terrell
patent: 3535388 (1971-09-01), Terrell
patent: 3897502 (1975-07-01), Russell et al.
patent: 3970710 (1976-07-01), Wolownik
patent: 3980714 (1976-09-01), Siegemund et al.
patent: 3981927 (1976-09-01), Siegemund et al.
patent: 4220664 (1980-09-01), McCarty et al.
patent: 4262144 (1981-04-01), McCarty et al.
patent: 4273947 (1981-06-01), Novotny
patent: 4584303 (1986-04-01), Huang et al.
patent: 4590310 (1986-05-01), Townsend et al.
patent: 4762856 (1988-08-01), Terrell
patent: 4855511 (1989-08-01), Halpern et al.
Kendig et al., Anesthesiology, 39(5): 518-524 (1973.
Meinwald et al., Science, 251: 560-561 (1991).
Brown et al., British Journal of Anaesthesia, 59: 14-23 (1987).
Clark et al., Anesthesiology, 39(3): 261-270 (1973).
Eger, British Journal of Anaesthesia, 56: 71S-99S (1984).
Jones et al., British Journal of Anaethesia, 65: 11-15 (1990).
Jones et al., Anesthesie et Analgesie, 70: 3-7 (1990).
Christys et al., British Journal of Anaesthesia, 62: 624-627 (1989).
Yasuda et al., Anesthesie et Analgesie, 71: 240-248 (1990).
Koblin et al., Anesthesie et Analgesie, 60: 464-470 (1981).
Hymes, Anesthesie et Analgesie, 64: 367-368 (1985).
McGuire et al., Anaesthesia, 45: 124-127 (1990).
Holmes et al., Anesthesie et Analgesie, 71: 249-253 (1990).
Knight et al., Antimicrobial Agents and Chemotherapy, 20(3): 298-306 (1981).
Koblin et al., Anesthesiology, 54: 314-317 (1981).
Freye et al., Anaesthesist, 34: 670-674 (1985).
Terrell, et al., Journal of Medicinal Chemistry, 14(6): 517-519.

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