Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Reexamination Certificate
2005-04-15
2011-11-15
Azpuru, Carlos (Department: 1617)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
Reexamination Certificate
active
08057815
ABSTRACT:
The present invention provides novel compositions and methods for inhibiting restenosis, thrombosis, and/or inflammation in a patient undergoing a vascular intervention. More particularly, the present invention provides intravascular devices coated with one or more spleen tyrosine kinase (Syk) inhibitors. Methods for inhibiting restenosis, thrombosis, and/or inflammation in a patient by treatment with such intravascular devices are also provided. In addition, the present invention provides methods for treating sickle cell disease using Syk inhibitors.
REFERENCES:
patent: 5171217 (1992-12-01), March et al.
patent: 2005/0181008 (2005-08-01), Hunter et al.
Andre Patrick
Homcy Charles
Phillips David R.
Azpuru Carlos
Kilpatrick Townsend and Stockton LLP
Portola Pharmaceuticals Inc.
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