Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2003-03-11
2008-08-19
Wang, Shengjun (Department: 1617)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S382000, C514S381000, C514S424000, C514S438000
Reexamination Certificate
active
07414071
ABSTRACT:
The present invention provides a method of treating hypertension, liver failure, loss of patency of ductus arteriosus, glaucoma or ocular hypertension in a patient, comprising administering to the patient a therapeutically effective amount of a selective EP4receptor agonist of Formula Ior a prodrug thereof, a pharmaceutically acceptable salt of the selective EP4receptor agonist or prodrug or a stereoisomer or diastereomeric mixture of the EP4receptor agonist, prodrug or salt, wherein the variables X, Z, Q,, and R2are as defined in the specification.
REFERENCES:
patent: 6747054 (2004-06-01), Cameron et al.
patent: WO 00/38667 (2000-07-01), None
Cameron Kimberly O.
Knight, Jr. Delvin R.
Lefker Bruce A.
Hsu Wendy L.
Pfizer Inc.
Wang Shengjun
Zielinski Bryan C.
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