Methods of treatment with renalase (monoamine oxidase C)

Details Methods of treatment with renalase (monoamine oxidase C) Methods of treatment with renalase (monoamine oxidase C)

2006-11-21

2010-12-28

Saidha, Tekchand (Department: 1652)

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Oxidoreductases

C435S189000, C536S023200

Reexamination Certificate

active

07858084

ABSTRACT:
The present invention provides methods of using Monoamine Oxidase C (MAO-C), also known as renalase, as a therapeutic protein in its active and inactive forms. Administering inactive renalase protein to individuals with lower renalase levels can be used to provide them with an adequate pool of the protein that can be activated by the body as needed. Active renalase protein can be administered to individuals needing an immediate reduction of catecholamine levels. An inhibitor of renalase may be used to enhance adrenergic action.

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