Methods of treatment using anti-ErbB antibody-maytansinoid...

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S130100, C424S135100, C424S141100, C424S155100, C424S158100

Reexamination Certificate

active

07097840

ABSTRACT:
The application concerns methods of treatment using anti-ErbB receptor antibody-maytansinoid conjugates, and articles of manufacture suitable for use in such methods. In particular, the invention concerns ErbB receptor-directed cancer therapies, using anri-ErbB receptor antibody-maytansinoid conjugates.

REFERENCES:
patent: 3896111 (1975-07-01), Kupchan et al.
patent: 4137230 (1979-01-01), Hashimoto et al.
patent: 4151042 (1979-04-01), Higashide et al.
patent: 4248870 (1981-02-01), Miyashita et al.
patent: 4256746 (1981-03-01), Miyashita et al.
patent: 4260608 (1981-04-01), Miyashita et al.
patent: 4265814 (1981-05-01), Hashimoto et al.
patent: 4294757 (1981-10-01), Asai
patent: 4307016 (1981-12-01), Asai et al.
patent: 4308268 (1981-12-01), Miyashita et al.
patent: 4308269 (1981-12-01), Miyashita et al.
patent: 4309428 (1982-01-01), Miyashita et al.
patent: 4313946 (1982-02-01), Powell et al.
patent: 4315929 (1982-02-01), Freedman et al.
patent: 4317821 (1982-03-01), Miyashita et al.
patent: 4322348 (1982-03-01), Asai et al.
patent: 4331598 (1982-05-01), Hasegawa et al.
patent: 4361650 (1982-11-01), Asai et al.
patent: 4362663 (1982-12-01), Kida et al.
patent: 4364866 (1982-12-01), Asai et al.
patent: 4371533 (1983-02-01), Akimoto et al.
patent: 4424219 (1984-01-01), Hashimoto et al.
patent: 4450254 (1984-05-01), Isley et al.
patent: 4968603 (1990-11-01), Slamon et al.
patent: 5183884 (1993-02-01), Kraus et al.
patent: 5208020 (1993-05-01), Chari et al.
patent: 5217713 (1993-06-01), Iwasa et al.
patent: 5416064 (1995-05-01), Chari et al.
patent: 5480968 (1996-01-01), Kraus et al.
patent: 5514554 (1996-05-01), Bacus
patent: 5677171 (1997-10-01), Hudziak et al.
patent: 5705157 (1998-01-01), Greene
patent: 5725856 (1998-03-01), Hudziak
patent: 5747261 (1998-05-01), King et al.
patent: 5772997 (1998-06-01), Hudziak et al.
patent: 5783186 (1998-07-01), Arakawa et al.
patent: 5821337 (1998-10-01), Carter et al.
patent: 5824311 (1998-10-01), Green et al.
patent: 5837234 (1998-11-01), Gentile et al.
patent: 5840525 (1998-11-01), Vandlen et al.
patent: 5877305 (1999-03-01), Huston et al.
patent: 5968517 (1999-10-01), Duncan et al.
patent: 6022541 (2000-02-01), Senger et al.
patent: 6054297 (2000-04-01), Carter et al.
patent: 6436931 (2002-08-01), Chari et al.
Sliwkowski, M.X. et al., J. Biol. Chem. 269(20): 14661-14665, 1994.
Arteaga, C.L. et al., “p185c-erbB-2Signaling Enhances Cisplatin-induced Cytotoxicity in Human Breast Carcinoma Cells: Association between an oncogenic Receptor Tyrosine Kinase and Drug-induced DNA Repair,”Cancer Research,vol. 54, pp. 3758-3765 (1994).
Bacus, S.S. et al., “Tumor-inhibitory Monoclonal Antibodies to the HER-2/Neu Receptor Induce Differentiation of Human Breast Cancer Cells,”Cancer Research,vol. 52, pp. 2580-2589 (1992).
Fendly, B.M. et al., “Characterization of Murine Monoclonal Antibodies Reactive to Either the Human Epidermal Growth Factor Receptor of HER2
eu Gene Product,”Cancer Research,vol. 50, 1550-1558 (1990).
Hancock, M.C. et al., “A Monoclonal Antibody against the c-erbB-2 Protein Enhances the Cytotoxicity of cis-Diamminedichloroplatinum against Human Breast and Ovarian Tumor Cell Lines,” vol. 51, pp. 4575-4580 (1991).
Issell, B.F. et al., “Maytansine,”Cancer Treatment Reviews,vol. 5, pp. 199-207 (1978).
Kasprzyk, P.G. et al., “Therapy of an Animal Model of Human Gastric Cancer Using a Combination of Anti-erbB-2 Monoclonal Antibodies,”Cancer Research,vol. 52, pp. 2771-2776 (1992).
Kern, J.A. et al., “p185neuExpression in Human Lung Adenocarcinomas Predicts Shortened Survival,”Cancer Research,vol. 50, pp. 5184-5191 (1990).
Lewis, G.D. et al., “Growth Regulation of Human Breast and Ovarian Tumor Cells by Heregulin: Evidence for the Requirement of ErbB2 as a Critical Component in Mediating Heregulin Responsiveness,”Cancer Research,vol. 56, pp. 1457-1465 (1996).
Maier, L.A. et al., “Requirement for the Internalization of a Murine Monoclonal Antibody Directed against the HER-2
eu Gene Product c-erbB-2,”Cancer Research,vol. 51, pp. 5361-5369 (1991).
Park, Joo-Bae et al., “Amplification, Overexpression, and Rearrangement of the erbB-2 Protooncogene in Primary Human Stomach Carcinomas,”Cancer Research,vol. 49, pp. 6605-6609 (1989).
Database Chemabs Online! Chemical Abstracts Service, Columbus, Ohio, US; Skrepnik, Nebojsa et al.: “Effects of anti-erbB -2 (HER-2
eu) recombinant oncotoxin Ar209 on human non-small cell lung carcinoma grown orthotopically in athymic nude mice” retreived from STN Database accession No. 126:14452 XP002164007, abstract & Clin. Cancer Res. (1996), 2(11), 1851-1857.
Sarup, J.C. et al., “Characterization of an Anti-p185HER2Monoclonal Antibody that Stimulates Receptor Function and Inhibits Tumor Cell Growth,”Growth Regulation,vol. 1, pp. 72-82 (1991).
Shawver, L.K. et al., “Ligand-like Effects induced by Anti-c-erbB-2 Antibodies Do Not Correlate with and Are Not Required for Growth Inhibition of Human Carcinoma Cells,”Cancer Research,vol. 54, pp. 1367-1373 (1994).
Skrepnik, N. et al., “Effects of Anti-erbB2 (HER-2
eu) Recombinant Oncotoxin AR209 on Human Non-Small Cell Lung Carcinoma Grown Orthotopically in Athymic Nude Mice,”Clinical Cancer Research,vol. 2, pp. 1851-1857 (1996).
Vietta, E.S. et al., “Monoclonal Antibodies as Agonists: An Expanded Role for Their Use in Cancer Therapy,”Cancer Research,vol. 54, pp. 5301-5309 (1994).
Weiner, D.B. et al., “Expression of the neu Gene-encoded Protein (P185neu) in Human Non-Small Cell Carcinomas of the Lung,”Cancer Research,vol. 50, pp. 421-425 (1990).
Yokota, J. et al., “Amplification of c-erbB2 Oncogene in Human Adenocarcinomas in Vivo,”The Lancet,vol. 1, pp. 765-767 (1986).
Yonemura, Y. et al., “Evaluation of Immunoreactivity for erbB-2 Protein as a Marker of Poor Short Term Prognosis in Gastric Cancer,”Cancer Research,vol. 51, pp. 1034-1038 (1991).
Chari, RVJ “Targeted delivery of chemotherapeutics: tumor-activated prodrug therapy,” Advanced Drug Delivery Reviews 31:89-104 (1998).
Spector et al., “Study of the Biologic Effects of Lapatinib, a Reversible Inhibitor of ErbB1 and ErbB2 Tyrosine Kinases, on Tumor Growth and Survival Pathways in Patients With Advanced Malignancies,” Jour. of Clin. Onc. 23(11):2502-2512 (2005).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods of treatment using anti-ErbB antibody-maytansinoid... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods of treatment using anti-ErbB antibody-maytansinoid..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of treatment using anti-ErbB antibody-maytansinoid... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3676970

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.